2-AMINO-2-(4-METHOXYPHENYL)ACETIC ACID
Uses- Product Name
- 2-AMINO-2-(4-METHOXYPHENYL)ACETIC ACID
- CAS No.
- 19789-59-4
- Chemical Name
- 2-AMINO-2-(4-METHOXYPHENYL)ACETIC ACID
- Synonyms
- NSC 101476;BIO-FARMA BF000291;α-Aminohomoanisic acid;4-METHOXY PHENYLGLYCINE;H-Phg(4-Methoxy)-OH (Rs);()-4-METHOXYPHENYL GLYCIN;DL-p-Methoxyphenylglycine;RS-4-methoxyphenylglycine;alpha-Aminohomoanisic acid;N-(4-METHOXYPHENYL)-GLYCINE
- CBNumber
- CB8381903
- Molecular Formula
- C9H11NO3
- Formula Weight
- 181.19
- MOL File
- 19789-59-4.mol
2-AMINO-2-(4-METHOXYPHENYL)ACETIC ACID Property
- Melting point:
- 235 °C (sublm)
- Boiling point:
- 339.5±37.0 °C(Predicted)
- Density
- 1.246±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 2.09±0.10(Predicted)
- Appearance
- white solid
- InChI
- InChI=1S/C9H11NO3/c1-13-7-4-2-6(3-5-7)8(10)9(11)12/h2-5,8H,10H2,1H3,(H,11,12)
- InChIKey
- GXUAKXUIILGDKW-UHFFFAOYSA-N
- SMILES
- C1(C=CC(OC)=CC=1)C(N)C(=O)O
- CAS DataBase Reference
- 19789-59-4(CAS DataBase Reference)
Safety
- HS Code
- 2922500090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 4657-1-53
- Product name
- 2-Amino-2-(4-methoxyphenyl)Acetic Acid
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- AS24129-A
- Product name
- 2-Amino-2-(4-methoxyphenyl)acetic Acid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $97
- Updated
- 2021/12/16
- Product number
- 0184AB
- Product name
- 2-Amino-2-(4-methoxyphenyl)aceticacid
- Packaging
- 1g
- Price
- $120
- Updated
- 2021/12/16
- Product number
- AAA0000082
- Product name
- (+/-)-METHOXYPHENYL GLYCIN
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $246.75
- Updated
- 2021/12/16
- Product number
- 4657-1-53
- Product name
- 2-Amino-2-(4-methoxyphenyl)Acetic Acid
- Packaging
- 5G
- Price
- $250
- Updated
- 2021/12/16
2-AMINO-2-(4-METHOXYPHENYL)ACETIC ACID Chemical Properties,Usage,Production
Uses
Amino(4-methoxyphenyl)acetic acid can be used as a pharmaceutical synthesis intermediate.
Synthesis
2-Amino-2-(4-methoxyphenyl)acetic acid was prepared as follows: ketone (0.5 mmol) and HCOONH 4 (5 mmol) were dissolved in MeOH (2 ml) in a carousel reaction tube using ammonium formate. The mixture was then degassed and stirred at 80 C and under nitrogen for 10 min. Then HCOOH / NEt3 azeotrope (0.5 ml) and catalyst solution (1 ml) (prepared by dissolving 0.5 mol of catalyst in 1 ml of MeOH) were introduced. The resulting mixture was stirred at 80C for the time indicated. The reaction was quenched with water, alkalized with aqueous KOH and extracted with DCM. The solvent was then removed under vacuum. The crude product was dissolved in ethanol (10 ml) and then 6N HCl solution (5 ml) was added. The mixture was refluxed for 6 hours. The ethanol was then removed under vacuum and the aqueous layer obtained was washed with ethyl acetate to remove impurities. The aqueous layer was alkalized with KOH solution and extracted with DCM. The organic layers were combined and dried with sodium sulfate. The final product amino(4-methoxyphenyl)acetic acid was obtained after evaporation of the solvent under vacuum. The yield was 88%.
2-AMINO-2-(4-METHOXYPHENYL)ACETIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-AMINO-2-(4-METHOXYPHENYL)ACETIC ACID manufacturers
- Product
- tiraseMtiv 2-AMINO-2-(4-METHOXYPHENYL)ACETIC ACIDCK-2017357) 19789-59-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%
- Supply Ability
- 200KG
- Release date
- 2018-08-19