ChemicalBook > CAS DataBase List > (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylpropanamide

(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylpropanamide

Product Name
(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylpropanamide
CAS No.
2088032-52-2
Chemical Name
(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylpropanamide
Synonyms
Liothyronine Impurity 13;L-Thyroxine-N-methylamide;Levothyroxine Impurity 49;N-Methylamide Levothyroxine; Levothyroxine USP Impurity b;N-Methylamide Levothyroxine HCl;Levothyroxine N-Methylamide (USP);Levothyroxine Methyl Amide Impurity;(S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylpropanamid;(S)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-N-methylpropanamide
CBNumber
CB83886236
Molecular Formula
C16H14I4N2O3
Formula Weight
789.91184
MOL File
2088032-52-2.mol
More
Less

(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylpropanamide Property

Boiling point:
623.2±55.0 °C(Predicted)
Density 
2.448±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: Slightly soluble,PBS (pH 7.2): 0.20 mg/ml
form 
A solid
pka
6.90±0.25(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylpropanamide Chemical Properties,Usage,Production

Uses

(S)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-N-methylpropanamide is an impurity of levothyroxine. Levothyroxine is an impurity of Thyroxine (T425600), one of the thyroid hormones involved in the maintenance of metabolic homeostasis, synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine.

(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylpropanamide Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylpropanamide Suppliers

More
Less

View Lastest Price from (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylpropanamide manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Levothyroxine USP Impurity b 2088032-52-2
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
0.98
Supply Ability
10g
Release date
2024-04-26

2088032-52-2, (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylpropanamideRelated Search:


  • (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylpropanamide
  • N-Methylamide Levothyroxine
  • Levothyroxine N-Methylamide (USP)
  • Levothyroxine Impurity 49
  • (S)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-N-methylpropanamide
  • Levothyroxine USP Impurity b
  • N-Methylamide Levothyroxine HCl
  • L-Thyroxine-N-methylamide
  • Liothyronine Impurity 13
  • Benzenepropanamide, α-amino-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-, (αS)-
  • Levothyroxine Methyl Amide Impurity
  • (S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylpropanamid
  • 2088032-52-2