(D-PHE11,HIS12)-SAUVAGINE, FRAGMENT 11-40 TRIFLUOROACETATE SALT
- Product Name
- (D-PHE11,HIS12)-SAUVAGINE, FRAGMENT 11-40 TRIFLUOROACETATE SALT
- Chemical Name
- (D-PHE11,HIS12)-SAUVAGINE, FRAGMENT 11-40 TRIFLUOROACETATE SALT
- Synonyms
- Anti-SVG-30;ANTI-SVG-30 TRIFLUOROACETATE SALT;ANTISAUVAGINE-30 TRIFLUOROACETATE SALT;(D-PHE11,HIS12)-SAUVAGINE, FRAGMENT 11-40 TRIFLUOROACETATE SALT;Anti-SVG-30, (D-Phe11,His12)-Sauvagine, Fragment 11-40 trifluoroacetate salt;D-PHE-HIS-LEU-LEU-ARG-LYS-MET-ILE-GLU-ILE-GLU-LYS-GLN-GLU-LYS-GLU-LYS-GLN-GLN-ALA-ALA-ASN-ASN-ARG-LEU-LEU-LEU-ASP-THR-ILE-NH2 TFA SALT
- CBNumber
- CB8392024
- Molecular Formula
- C163H276F3N49O47S
- Formula Weight
- 3763.3
- MOL File
- Mol file
(D-PHE11,HIS12)-SAUVAGINE, FRAGMENT 11-40 TRIFLUOROACETATE SALT Property
- storage temp.
- -20°C
- solubility
- Water: soluble
- form
- powder
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- A4727
- Product name
- Antisauvagine-30 trifluoroacetate salt
- Packaging
- 1mg
- Price
- $1197
- Updated
- 2025/07/31
- Product number
- A697550
- Product name
- Antisauvagine-30 trifluoroacetate salt
- Packaging
- 0.5mg
- Price
- $605
- Updated
- 2021/12/16
- Product number
- HCH0066720
- Product name
- ANTISAUVAGINE-30 TRIFLUOROACETATE SALT
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $1480.77
- Updated
- 2021/12/16
(D-PHE11,HIS12)-SAUVAGINE, FRAGMENT 11-40 TRIFLUOROACETATE SALT Chemical Properties,Usage,Production
Uses
Antisauvagine-30 Trifluoroacetate Salt is a CRF1 and CRF2 antagonist blocking secretions of cortisol and adrenocorticotropic hormone (ACTH). Used in studies involving stress and memory.
Biochem/physiol Actions
High-affinity antagonist for Corticotropin-releasing factor (CRF) receptor type 2 (CRF(2)).
References
[1] F M DAUTZENBERG. Different binding modes of amphibian and human corticotropin-releasing factor type 1 and type 2 receptors: evidence for evolutionary differences.[J]. Journal of Pharmacology and Experimental Therapeutics, 2001, 296 1: 113-120.
[2] A RÜHMANN. Structural requirements for peptidic antagonists of the corticotropin-releasing factor receptor (CRFR): development of CRFR2beta-selective antisauvagine-30.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1998, 95 26: 15264-15269. DOI: 10.1073/pnas.95.26.15264
[3] F. SANANBENESI. Mitogen-Activated Protein Kinase Signaling in the Hippocampus and Its Modulation by Corticotropin-Releasing Factor Receptor 2: A Possible Link between Stress and Fear Memory[J]. The Journal of Neuroscience, 2003, 16 1: 11436-11443. DOI: 10.1523/jneurosci.23-36-11436.2003
[4] MARCELA CRISTINA GARNICA-SIQUEIRA . Corticotrophin-releasing factor mediates vasoactive intestinal peptide-induced hypophagia and changes in plasma parameters[J]. Hormones and Behavior, 2018, 105: Pages 138-145. DOI: 10.1016/j.yhbeh.2018.08.008
(D-PHE11,HIS12)-SAUVAGINE, FRAGMENT 11-40 TRIFLUOROACETATE SALT Preparation Products And Raw materials
Raw materials
Preparation Products
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