ChemicalBook > CAS DataBase List > ex229 (compound 991)

ex229 (compound 991)

Product Name: ex229 (compound 991)
CAS No.: 1219739-36-2
Chemical Name: ex229 (compound 991)
Synonyms: EX229;EX-229;EX 229;EX229;ex229 (compound 991);EX229, 10 mM in DMSO;AMPK Activator 991 (Compound 991);AMP-activated protein kinase,inhibit,EX 229,AMPK,Inhibitor,EX-229,EX229;5-{[6-chloro-5-(1-methyl-1H-indol-5-yl)-1H-benzimidazol-2-yl]oxy}-2-methylbenzoic acid;5-[[6-Chloranyl-5-(1-Methylindol-5-Yl)-1h-Benzimidazol-2-Yl]oxy]-2-Methyl-Benzoic Acid;Benzoic acid, 5-[[6-chloro-5-(1-methyl-1H-indol-5-yl)-1H-benzimidazol-2-yl]oxy]-2-methyl-
CBNumber: CB83960141
Molecular Formula: C24H18ClN3O3
Formula Weight: 431.87
MOL File: 1219739-36-2.mol

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ex229 (compound 991) Property

Boiling point:: 706.4±70.0 °C(Predicted)
Density: 1.41±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.30 mg/ml
form: A solid
pka: 3.40±0.25(Predicted)
color: Off-white to pink

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0063368
Product name: EX229
Purity: 98.37%
Packaging: 5mg
Price: $80
Updated: 2021/12/16

ChemScene

Product number: CS-0063368
Product name: EX229
Purity: 98.37%
Packaging: 10mg
Price: $140
Updated: 2021/12/16

ChemScene

Product number: CS-0063368
Product name: EX229
Purity: 98.37%
Packaging: 25mg
Price: $290
Updated: 2021/12/16

ChemScene

Product number: CS-0063368
Product name: EX229
Purity: 98.37%
Packaging: 50mg
Price: $490
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573154
Product name: EX-229
Purity: >98%
Packaging: 100mg
Price: $1060.8
Updated: 2021/12/16

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ex229 (compound 991) Chemical Properties,Usage,Production

Uses

AMPK Activator 991 is a small benzimidazole derivative that potently activates AMP-activated protein kinase (AMPK) to increase glucose transport in skeletal muscle, with possible applications in treating a variety of metabolic disorders, such as Type 2 diabetes.

IC 50

AMPK α1β1γ1: 0.06 μM (Kd); AMPK α2β1γ1: 0.06 μM (Kd); AMPK α1β2γ1: 0.51 μM (Kd)

ex229 (compound 991) Preparation Products And Raw materials

Raw materials

Preparation Products

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1219739-36-2, ex229 (compound 991)Related Search:

ex229 (compound 991)

EX229

EX-229

5-{[6-chloro-5-(1-methyl-1H-indol-5-yl)-1H-benzimidazol-2-yl]oxy}-2-methylbenzoic acid

EX 229;EX229

Benzoic acid, 5-[[6-chloro-5-(1-methyl-1H-indol-5-yl)-1H-benzimidazol-2-yl]oxy]-2-methyl-

5-[[6-Chloranyl-5-(1-Methylindol-5-Yl)-1h-Benzimidazol-2-Yl]oxy]-2-Methyl-Benzoic Acid

AMPK Activator 991 (Compound 991)

AMP-activated protein kinase,inhibit,EX 229,AMPK,Inhibitor,EX-229,EX229

5-((6-Chloro-5-(1-methyl-1H-indol-5-yl)-1H-benzo[d]imidazol-2-yl)oxy)-2-methylbenzoic acid

5-{[6-chloro-5-(1-methyl-1H-indol-5-yl)-1H-1,3-benzodiazol-2-yl]oxy}-2-methylbenzoic acid

EX229, 10 mM in DMSO

1219739-36-2

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