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Brassicasterol

Product Name
Brassicasterol
CAS No.
474-67-9
Chemical Name
Brassicasterol
Synonyms
ERGOSTA-5,22-DIEN-3-OL;5,22-Cholestadien-24β-methyl-3β-ol;(22E,24R)-24-Methylcholesta-5,22-dien-3β-ol;Brassicaterol;BRASSICASTEROL;Brassicasterin;BRASSICASTEROL(P);BRASSICASTEROL(SG);Δ5,22-Ergostadienol;DELTA5,22-Ergostadienol
CBNumber
CB8396800
Molecular Formula
C28H46O
Formula Weight
398.66
MOL File
474-67-9.mol
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Brassicasterol Property

Melting point:
205-213℃
Boiling point:
488.7±14.0 °C(Predicted)
Density 
0.99±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Solid
pka
15.03±0.70(Predicted)
color 
White to Off-White
InChIKey
OILXMJHPFNGGTO-FFCHNKSWNA-N
SMILES
[C@@]12([H])CC[C@H]([C@H](C)/C=C/[C@H](C)C(C)C)[C@@]1(C)CC[C@]1([H])[C@@]3(C)CC[C@H](O)CC3=CC[C@@]21[H] |&1:0,4,5,9,14,18,20,24,30,r|
LogP
9.679 (est)
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Safety

WGK Germany 
3
HS Code 
29061310
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B4936
Product name
Brassicasterol
Purity
from semisynthetic
Packaging
5mg
Price
$544
Updated
2024/03/01
Cayman Chemical
Product number
22296
Product name
Brassicasterol
Purity
≥95%
Packaging
1mg
Price
$86
Updated
2024/03/01
Cayman Chemical
Product number
22296
Product name
Brassicasterol
Purity
≥95%
Packaging
5mg
Price
$399
Updated
2024/03/01
Cayman Chemical
Product number
22296
Product name
Brassicasterol
Purity
≥95%
Packaging
10mg
Price
$671
Updated
2024/03/01
TRC
Product number
B676850
Product name
Brassicasterol
Packaging
5mg
Price
$130
Updated
2021/12/16
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Brassicasterol Chemical Properties,Usage,Production

Uses

Brassicasterol was used as standard to analyze the sterols from mussels sample by thin layer chromatography.

Uses

A phytosterol found in canola oil, rapeseed oil, marine algae and shellfish. This compound has been shown to inhibit sterol Δ24-reductase, an enzyme involved in the mammalian cholesterol biosynthesis pathway.

Definition

ChEBI: Brassicasterol is an 3beta-sterol that is (22E)-ergosta-5,22-diene substituted by a hydroxy group at position 3beta. It is a phytosterol found in marine algae, fish, and rapeseed oil. It has a role as an EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitor, a biomarker, a human metabolite, a plant metabolite, an animal metabolite, an algal metabolite, a sterol biosynthesis inhibitor and a marine metabolite. It is an ergostanoid, a 3beta-sterol, a member of phytosterols and a 3beta-hydroxy-Delta(5)-steroid.

General Description

Brassicasterol is a plant sterol, sharing similar structure with cholesterol. It is obtained through the dietary sources, including sea food.

Biochem/physiol Actions

Brassicasterol is a plant sterol, structurally similar to cholesterol. Plant sterols compete with cholesterol and reduce the content of cholesterol incorporated into micelles thereby reducing its absorption. Brassicasterol reportedly decreases the progression of atherosclerosis. The level of brassicasterol in cerebrospinal fluid may be used as a prognostic factor for progression of Alzheimer′s disease.

Side effects

Plant sterols are LIKELY SAFE for most people when taken by mouth. They can cause some side effects, such as diarrhea or fat in the stool.

Precautions

Sitosterolemia, a rare inherited fat storage disease: Plant sterols can build up in the blood and tissue of people with this condition. This build-up can make these people prone to early heart disease. Taking plant sterols might make this condition worse. Don't take plant sterols if you have sitosterolemia.
Short bowel syndrome, a condition related to removal of part of the gut: Worsening of liver function has been reported for a person with short bowel syndrome who was given nutrients containing plant sterols. Liver function improved when the plant sterols were removed from the nutrients. It's not clear if the plant sterols were responsible. Until more is known, don't take plant sterols if you have short bowel syndrome.    

Brassicasterol Preparation Products And Raw materials

Raw materials

Preparation Products

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Brassicasterol Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4940
Advantage
60
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
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60
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Yichang Zhongyitai Trading Co., Ltd.
Tel
0717-6449896 13886658719
Fax
0717-6558598
Email
root@zhongyitai.com
Country
China
ProdList
1977
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18070
Advantage
56
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7887
Advantage
56
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View Lastest Price from Brassicasterol manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Brassicasterol 474-67-9
Price
US $1.00-22.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100000KG
Release date
2024-08-02

474-67-9, BrassicasterolRelated Search:


  • (22E)-Ergosta-5,22-dien-3-ol
  • Brassicasterin
  • DELTA5,22-Ergostadien-3beta-ol
  • DELTA5,22-Ergostadienol
  • Ergosta-5,22-dien-3beta-ol
  • Ergosta-5,22-dien-3-ol, (3beta,22E)-
  • 5, 22-CHOLESTADIEN-24BETA-METHYL-3BETA-OL
  • 5,22-CHOLESTANDIEN-24B-METHYL-3B-OL
  • ERGOSTA-5,22-DIEN-3-OL
  • BRASSICASTEROL
  • Ergosta-5,22-dien-3-ol,(3.
  • BRASSICASTEROL, SOLUTION IN METHYLENE CHLORIDE
  • 5,22-Cholestadien-24β-methyl-3β-ol
  • ergosta-5,22(E)-dien-3beta-ol
  • Brassicaterol
  • Ergosta-5,22-dien-3-ol,(3b,22E)-
  • (22E,24R)-22,23-Didehydro-24-methylcholesterol
  • (22E,24R)-24-Methylcholesta-5,22-dien-3β-ol
  • BRASSICASTEROL(SG)
  • Brassicasterol,5,22-Cholestadien-24β-methyl-3β-ol
  • (3β,22E)-Ergosta-5,22-dien-3-ol
  • 24(R)-Methylcholesta-5,22E-dien-3β-ol
  • Ergosta-5,22(E)-dien-3β-ol
  • Δ5,22-Ergostadien-3β-ol
  • Δ5,22-Ergostadienol
  • BRASSICASTEROL(P)
  • Brassicasterol, 98%, from cuscuta chinensis Lam.
  • Ergosta-5,22-dien-3-ol, (3β,22E)-
  • 5, 22-CHOLESTADIEN-24β-METHYL-3β-OL
  • BRASSICASTEROL(P) 100mg
  • 474-67-9
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids