2,3-DIMETHYL-6,7-DIMETHOXYQUINOXALINE
- Product Name
- 2,3-DIMETHYL-6,7-DIMETHOXYQUINOXALINE
- CAS No.
- 32388-00-4
- Chemical Name
- 2,3-DIMETHYL-6,7-DIMETHOXYQUINOXALINE
- Synonyms
- 139976;6,7-Dimethoxy-2,3-dimethylquinoxaline;2,3-DIMETHYL-6,7-DIMETHOXYQUINOXALINE;Quinoxaline,6,7-dimethoxy-2,3-dimethyl-;2,3-Dimethyl-6,7-dimethoxyquinoxaline 98%
- CBNumber
- CB8402349
- Molecular Formula
- C12H14N2O2
- Formula Weight
- 218.25
- MOL File
- 32388-00-4.mol
2,3-DIMETHYL-6,7-DIMETHOXYQUINOXALINE Property
- Melting point:
- 176-178°C
- Boiling point:
- 327.0±37.0 °C(Predicted)
- Density
- 1.145±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform
- form
- Solid
- pka
- 1.60±0.48(Predicted)
- color
- Off-White to Pale Yellow
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D460673
- Product name
- 6,7-Dimethoxy-2,3-dimethyl-quinoxaline
- Packaging
- 10mg
- Price
- $140
- Updated
- 2021/12/16
- Product number
- 4H08-1-17
- Product name
- 2,3-Dimethyl-6,7-dimethoxyquinoxaline
- Packaging
- 100mg
- Price
- $194
- Updated
- 2021/12/16
- Product number
- 4H08-1-17
- Product name
- 2,3-Dimethyl-6,7-dimethoxyquinoxaline
- Packaging
- 250mg
- Price
- $309
- Updated
- 2021/12/16
- Product number
- 3607AB
- Product name
- 6,7-Dimethoxy-2,3-dimethylquinoxaline
- Packaging
- 250mg
- Price
- $325
- Updated
- 2021/12/16
- Product number
- FD22172
- Product name
- 6,7-Dimethoxy-2,3-dimethyl-quinoxaline
- Packaging
- 25mg
- Price
- $463
- Updated
- 2021/12/16
2,3-DIMETHYL-6,7-DIMETHOXYQUINOXALINE Chemical Properties,Usage,Production
Chemical Properties
Off-White to Pale Yellow Solid
Uses
6,7-Dimethoxy-2,3-dimethyl-quinoxaline (cas# 32388-00-4) is a compound useful in organic synthesis.
Synthesis
7595-31-5
431-03-8
32388-00-4
General procedure: 4,5-dimethoxy-2-nitroaniline (1.0 mmol), 2,3-butanedione (1.0 or 2.0 mmol), indium powder (0.574 g, 5.0 mmol) and acetic acid (0.300 g, 5 mmol or 0.600 g, 10 mmol) or indium chloride (0.221 g, 1 mmol or 0.265 g, 1.2 mmol) were dissolved in methanol (5 mL) or toluene (5 mL). The reaction mixture was stirred at 50°C, 80°C or 50°C under nitrogen protection. After completion of the reaction, the reaction mixture was diluted with ethyl acetate (30 mL), filtered through diatomaceous earth, and the filtrate was poured into 10% NaHCO3 solution (30 mL) and extracted with ethyl acetate (30 mL x 3). The organic phases were combined, dried with anhydrous MgSO4, filtered and concentrated. The residue was purified by silica gel column chromatography with ethyl acetate/hexane (v/v 10/90) as eluent to give purified 6,7-dimethoxy-2,3-dimethylquinoxaline. The product structure was confirmed by 1H NMR, 13C NMR, FTIR and GC-MS characterization. For unknown compounds, elemental analysis is also required. 4.2.1. Synthesis of 6,7-dimethoxy-2,3-dimethylquinoxaline (5): 87% yield. Yellow solid, melting point 109-110°C (literature value 105°C).TLC (10% ethyl acetate/hexane) Rf 0.30; 1H NMR (400 MHz, CDCl3) δ 7.91 (dd, 2H, J=6.3, 3.5 Hz), 7.59 (dd, 1H, J=6.3, 3.5 Hz), 2.66 (s, 6H); 13C NMR (100 MHz, CDCl3) δ 153.4, 141.0, 128.7, 128.2, 23.1; IR (KBr) 3109, 3078, 3030, 2995, 2953, 2914, 1490, 1398, 1164 cm-1; GC-MS m/z (relative intensity) 158 (M+, 99) , 117 (100), 76 (28), 50 (12).
References
[1] Tetrahedron, 2015, vol. 71, # 8, p. 1215 - 1226
2,3-DIMETHYL-6,7-DIMETHOXYQUINOXALINE Preparation Products And Raw materials
Raw materials
Preparation Products
2,3-DIMETHYL-6,7-DIMETHOXYQUINOXALINE Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- 0510-83588313-811 18800520310
- sales@chemshuttle.com
- Country
- China
- ProdList
- 2999
- Advantage
- 62
- Tel
- 18270980682
- Fax
- 021 51613951
- mlcheng@sunwaypharm.cn
- Country
- China
- ProdList
- 8669
- Advantage
- 57
- Tel
- 021-60343070
- Fax
- 021-35122006
- Country
- China
- ProdList
- 12740
- Advantage
- 55
- Tel
- 021-61478794
- Fax
- 021-61478794
- sales@hcshhai.com
- Country
- China
- ProdList
- 9793
- Advantage
- 50
- Tel
- 021-58892003
- info@qiaochem.com
- Country
- China
- ProdList
- 6059
- Advantage
- 65
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 025-58851090 15955137747
- Fax
- (6)02557626880
- sales01@aikonchem.com
- Country
- China
- ProdList
- 15949
- Advantage
- 58
- Tel
- +86-400-002-6226 +86-13028896684;
- sales@rrkchem.com
- Country
- China
- ProdList
- 57422
- Advantage
- 58