ChemicalBook > CAS DataBase List > H-THR-PHE-ARG-GLY-ALA-PRO-OH

H-THR-PHE-ARG-GLY-ALA-PRO-OH

Product Name: H-THR-PHE-ARG-GLY-ALA-PRO-OH
CAS No.: 320347-28-2
Chemical Name: H-THR-PHE-ARG-GLY-ALA-PRO-OH
Synonyms: TFRGAP;PAR-3 (1-6) (HUMAN);THR-PHE-ARG-GLY-ALA-PRO;H-THR-PHE-ARG-GLY-ALA-PRO-OH;Protease Activated Receptor-3 (1-6);THROMBIN RECEPTOR-LIKE 2 (1-6) (HUMAN);PROTEINASE ACTIVATED RECEPTOR 3 (1-6) (HUMAN);COAGULATION FACTOR II RECEPTOR-LIKE 2 (1-6) (HUMAN);L-Threonyl-L-phenylalanyl-L-arginylglycyl-L-alanyl-L-proline;L-Proline, L-threonyl-L-phenylalanyl-L-arginylglycyl-L-alanyl-
CBNumber: CB8402884
Molecular Formula: C29H45N9O8
Formula Weight: 647.72
MOL File: Mol file

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H-THR-PHE-ARG-GLY-ALA-PRO-OH Property

storage temp.: -15°C
solubility: DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 10 mg/ml
form: A crystalline solid
Sequence: Thr-Phe-Arg-Gly-Ala-Pro

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 27129
Product name: PAR3 (1-6) (human)
Packaging: 1mg
Price: $116
Updated: 2024/03/01

Cayman Chemical

Product number: 27129
Product name: PAR3 (1-6) (human)
Packaging: 5mg
Price: $502
Updated: 2024/03/01

Cayman Chemical

Product number: 27129
Product name: PAR3 (1-6) (human)
Packaging: 500μg
Price: $68
Updated: 2024/03/01

American Custom Chemicals Corporation

Product number: PEP0011735
Product name: PAR-3 (1-6) (HUMAN)
Purity: 95.00%
Packaging: 5MG
Price: $500.19
Updated: 2021/12/16

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H-THR-PHE-ARG-GLY-ALA-PRO-OH Chemical Properties,Usage,Production

Uses

PAR3 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 1 (PAR1) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR3 and residues 39-44 of the full-length human sequence. PAR3 (1-6) activates p42/44 MAPK signaling in fibroblasts expressing PAR1, but not PAR3, an effect that can be blocked by the PAR1 antagonist RWJ 56110.

References

[1] Kaufmann, et al. Proteinase-activated receptors (PARs) - The PAR3 neo-N-terminal peptide TFRGAP interacts with PAR1. Regul. Pept. 125(1-3), 61-66 (2005).

H-THR-PHE-ARG-GLY-ALA-PRO-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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320347-28-2, H-THR-PHE-ARG-GLY-ALA-PRO-OHRelated Search:

H-THR-PHE-ARG-GLY-ALA-PRO-OH

PROTEINASE ACTIVATED RECEPTOR 3 (1-6) (HUMAN)

PAR-3 (1-6) (HUMAN)

TFRGAP

THROMBIN RECEPTOR-LIKE 2 (1-6) (HUMAN)

H-THR-PHE-ARG-GLY-ALA-PRO-OH

COAGULATION FACTOR II RECEPTOR-LIKE 2 (1-6) (HUMAN)

THR-PHE-ARG-GLY-ALA-PRO

Coagulation Factor II Receptor-Like 2 (1-6) (huMan), Proteinase Activated Receptor 3 (1-6) (huMan), ThroMbin Receptor-Like 2 (1-6) (huMan), TFRGAP

L-Proline, L-threonyl-L-phenylalanyl-L-arginylglycyl-L-alanyl-

L-Threonyl-L-phenylalanyl-L-arginylglycyl-L-alanyl-L-proline

Protease Activated Receptor-3 (1-6)

320347-28-2

C29H45N9O8