ChemicalBook > CAS DataBase List > 2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE
2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE
- Product Name
- 2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE
- CAS No.
- 139047-55-5
- Chemical Name
- 2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE
- Synonyms
- 3-MPPI;2-PMDQ;2 PMDQ,2PMDQ;2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE;Imidazo[1,2-c]quinazolin-5(3H)-one, 2,6-dihydro-2-[(4-phenyl-1-piperazinyl)methyl]-
- CBNumber
- CB8409227
- Molecular Formula
- C21H23N5O
- Formula Weight
- 361.44
- MOL File
- Mol file
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2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE Property
- Density
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- Store at RT
- solubility
- Soluble to 10 mM in DMSO and in ethanol
- form
- Powder
- pka
- 13.74±0.40(Predicted)
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N-Bromosuccinimide Price
TRC
- Product number
- P637005
- Product name
- 2-PMDQ
- Packaging
- 10mg
- Price
- $165
- Updated
- 2021/12/16
Usbiological
- Product number
- 254372
- Product name
- 2-PMDQ
- Packaging
- 10mg
- Price
- $418
- Updated
- 2021/12/16
TRC
- Product number
- P637005
- Product name
- 2-PMDQ
- Packaging
- 50mg
- Price
- $670
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B6382
- Product name
- 2-PMDQ
- Packaging
- 10mg
- Price
- $171
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- INB0004260
- Product name
- 2-PMDQ
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.89
- Updated
- 2021/12/16
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2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE Chemical Properties,Usage,Production
Uses
2-PMDQ is an analog of Ketanserin with beneficial hemodynamic effects in portal hypertensive rats. Anti-hypertensive effects.
Definition
ChEBI: 2-[(4-phenyl-1-piperazinyl)methyl]-3,6-dihydro-2H-imidazo[1,2-c]quinazolin-5-one is a member of piperazines.
Biological Activity
Very potent ligand for α 1 sites (K i for displacement of prazosin = 0.2 nM). Also binds to 5-HT 1A sites (K i = 50 nM).
2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
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2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE Suppliers
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