1-STEAROYL-2-ARACHIDONOYL-PHOSPHATIDYLINOSITOL 3,4,5-TRIPHOSPHATE, (NA+ SALT)
- Product Name
- 1-STEAROYL-2-ARACHIDONOYL-PHOSPHATIDYLINOSITOL 3,4,5-TRIPHOSPHATE, (NA+ SALT)
- Chemical Name
- 1-STEAROYL-2-ARACHIDONOYL-PHOSPHATIDYLINOSITOL 3,4,5-TRIPHOSPHATE, (NA+ SALT)
- Synonyms
- C-20:4;SAPI-3,4,5-P3 (NA+ SALT);PHOSPHATIDYLINOSITOL-3,4,5-TRIPHOSPHATE C-18 SODIUM SALT;PTDINS-(3,4,5)-P3 (1-STEAROYL, 2-ARACHIDONOYL) SODIUM SALT;1-STEAROYL-2-ARACHIDONOYL-PHOSPHATIDYLINOSITOL 3,4,5-TRIPHOSPHATE, (NA+ SALT);1-(1-OCTADECANOYL-2R-(5Z,8Z,11Z,14Z)-EICOSATETRAENOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEPTASODIUM SALT
- CBNumber
- CB8417615
- Molecular Formula
- C47H79Na7O22P4
- Formula Weight
- 1280.94
- MOL File
- Mol file
1-STEAROYL-2-ARACHIDONOYL-PHOSPHATIDYLINOSITOL 3,4,5-TRIPHOSPHATE, (NA+ SALT) Property
- solubility
- CHCl3:CH3OH:H2O (3:2:1): 10 mg/mlPBS (pH 7.2): Freely soluble
N-Bromosuccinimide Price
- Product number
- 64930
- Product name
- PtdIns-(3,4,5)-P3 (1-stearoyl, 2-arachidonoyl) (sodium salt)
- Packaging
- 50μg
- Price
- $89
- Updated
- 2024/03/01
- Product number
- 64930
- Product name
- PtdIns-(3,4,5)-P3 (1-stearoyl, 2-arachidonoyl) (sodium salt)
- Packaging
- 1mg
- Price
- $1188
- Updated
- 2024/03/01
- Product number
- 64930
- Product name
- PtdIns-(3,4,5)-P3 (1-stearoyl, 2-arachidonoyl) (sodium salt)
- Packaging
- 100μg
- Price
- $168
- Updated
- 2024/03/01
- Product number
- 64930
- Product name
- PtdIns-(3,4,5)-P3 (1-stearoyl, 2-arachidonoyl) (sodium salt)
- Packaging
- 500μg
- Price
- $700
- Updated
- 2024/03/01
1-STEAROYL-2-ARACHIDONOYL-PHOSPHATIDYLINOSITOL 3,4,5-TRIPHOSPHATE, (NA+ SALT) Chemical Properties,Usage,Production
Description
PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and Akts are examples of PtdIns-(3,4,5)-P3-binding proteins.1,2 Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific PLC. Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. For further reading on inositol phospholipids, see also references 3 and 4.WARNING This product is not for human or veterinary use.
References
[1] KENICHI TANAKA. A Target of Phosphatidylinositol 3,4,5-Trisphosphate with a Zinc Finger Motif Similar to that of the ADP-Ribosylation-Factor GTPase-Activating Protein and Two Pleckstrin Homology Domains[J]. The FEBS journal, 2004, 245 2: 512-519. DOI: 10.1111/j.1432-1033.1997.00512.x
[2] X YANG. Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate.[J]. The Journal of Biological Chemistry, 1999, 274 27: 18973-18980. DOI: 10.1074/jbc.274.27.18973
[3] L J PIKE L C. Localization and turnover of phosphatidylinositol 4,5-bisphosphate in caveolin-enriched membrane domains.[J]. The Journal of Biological Chemistry, 1996, 271 43: 26453-26456. DOI: 10.1074/jbc.271.43.26453
[4] BERRIDGE M J. Inositol trisphosphate and calcium signalling[J]. Nature, 1993, 361 6410: 315-325. DOI: 10.1038/361315a0
1-STEAROYL-2-ARACHIDONOYL-PHOSPHATIDYLINOSITOL 3,4,5-TRIPHOSPHATE, (NA+ SALT) Preparation Products And Raw materials
Raw materials
Preparation Products
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