ChemicalBook > CAS DataBase List > b-D-Glucopyranosyl-1,1'-N-Docosanoyl-2'-Docosanamide-4'-octadecene-1',3'-diol

b-D-Glucopyranosyl-1,1'-N-Docosanoyl-2'-Docosanamide-4'-octadecene-1',3'-diol

Product Name
b-D-Glucopyranosyl-1,1'-N-Docosanoyl-2'-Docosanamide-4'-octadecene-1',3'-diol
CAS No.
119242-44-3
Chemical Name
b-D-Glucopyranosyl-1,1'-N-Docosanoyl-2'-Docosanamide-4'-octadecene-1',3'-diol
Synonyms
22:0);C22 Glucosylceramide (d18:1/22:0);b-D-Glucopyranosyl-1,1'-N-Docosanoyl-2'-Docosanamide-4'-octadecene-1',3'-diol;N-[(1S,2R,3E)-1-[(β-D-glucopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-docosanamide;Docosanamide, N-[(1S,2R,3E)-1-[(β-D-glucopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-
CBNumber
CB84204198
Molecular Formula
C46H89NO8
Formula Weight
784.201
MOL File
119242-44-3.mol
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b-D-Glucopyranosyl-1,1'-N-Docosanoyl-2'-Docosanamide-4'-octadecene-1',3'-diol Property

Boiling point:
887.4±65.0 °C(Predicted)
Density 
1.03±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Chloroform: Soluble
form 
A solid
pka
12.92±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
23210
Product name
C22 Glucosylceramide (d18:1/22:0)
Purity
>98%
Packaging
1mg
Price
$517
Updated
2024/03/01
AK Scientific
Product number
7040CR
Product name
Glucosylceramide(d18:1/22:0)
Packaging
1mg
Price
$700
Updated
2021/12/16
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b-D-Glucopyranosyl-1,1'-N-Docosanoyl-2'-Docosanamide-4'-octadecene-1',3'-diol Chemical Properties,Usage,Production

Description

C22 Glucosylceramide is an endogenous glucosylceramide.1,2,3 Glucosylceramides are major constituents of skin lipid membranes where they play a role in maintaining the water permeability barrier. They are precursors in the synthesis of lactosylceramide , as well as oligoglycolipids and gangliosides. Phospholipase A2 (PLA2) type XIIA knockdown increases C22 glucosylceramide expression in rat brain.3 It is also increased in the brain, but not the liver or spinal cord, of mice fed a methionine-restricted diet.2 In human athletes, plasma levels of C22 glucosylceramide increase during exercise and return to basal levels during recovery.1 This product contains C22 glucosylceramide isolated from bovine buttermilk. As this product is derived from a natural source, there may be variations in the sphingoid backbone.

Definition

ChEBI: Beta-D-glucosyl-N-(docosanoyl)sphingosine is a beta-D-glucosylceramide where the ceramide N-acyl group is specified as docosanoyl. It has a role as a mouse metabolite. It is functionally related to a docosanoic acid.

References

1. Bergman, B.C., Brozinick, J.T., Strauss, A., et al. Serum sphingolipids: Relationships to insulin sensitivity and changes with exercise in humans Am. J. Physiol. Endocrinol. Metab. 309(4),E398-E408(2015).
2. Jové, M., Ayala, V., Ramírez-Nú?ez, O., et al. Specific lipidome signatures in central nervous system from methionine-restricted mice J. Proteome Res. 12(6),2679-2689(2013).
3. Ee, S.-M., Lo, Y.-L., Shui, G., et al. Distribution of secretory phospholipase A2 XIIA in the brain and its role in lipid metabolism and cognition Mol. Neurobiol. 50(1),60-75(2014).

b-D-Glucopyranosyl-1,1'-N-Docosanoyl-2'-Docosanamide-4'-octadecene-1',3'-diol Preparation Products And Raw materials

Raw materials

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b-D-Glucopyranosyl-1,1'-N-Docosanoyl-2'-Docosanamide-4'-octadecene-1',3'-diol Suppliers

China 11 United States 4 Global 15
Yichang Zhongyitai Trading Co., Ltd.
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119242-44-3, b-D-Glucopyranosyl-1,1'-N-Docosanoyl-2'-Docosanamide-4'-octadecene-1',3'-diolRelated Search:


  • b-D-Glucopyranosyl-1,1'-N-Docosanoyl-2'-Docosanamide-4'-octadecene-1',3'-diol
  • C22 Glucosylceramide (d18:1/22:0)
  • Docosanamide, N-[(1S,2R,3E)-1-[(β-D-glucopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-
  • N-[(1S,2R,3E)-1-[(β-D-glucopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-docosanamide
  • 22:0)
  • 119242-44-3