2-Hexylthiophene
- Product Name
- 2-Hexylthiophene
- CAS No.
- 18794-77-9
- Chemical Name
- 2-Hexylthiophene
- Synonyms
- EA123;2-n-HexyL;FEMA 4137;-Hexylthiophene;2-hexyl-thiophen;Einecs 242-579-4;2-HEXYLTHIOPHENE;trans-2-Butene-1;2-N-HEXYLTHIOPHENE;2-Hexylthiophene>
- CBNumber
- CB8424899
- Molecular Formula
- C10H16S
- Formula Weight
- 168.3
- MOL File
- 18794-77-9.mol
2-Hexylthiophene Property
- Melting point:
- -39.15°C (estimate)
- Boiling point:
- 228-230°C
- Density
- 0.932 g/mL at 25 °C
- refractive index
- 1.4960
- FEMA
- 4137 | 2-HEXYLTHIOPHENE
- Flash point:
- 107°C
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- Liquid
- color
- Colorless to light yellow
- Odor
- at 0.10 % in dipropylene glycol. floral fruity gassy green meaty
- Odor Type
- sulfurous
- Water Solubility
- Soluble in most organic solvents and ethanol Soluble . Insoluble in water.
- λmax
- 234nm(EtOH)(lit.)
- JECFA Number
- 1764
- BRN
- 110220
- InChIKey
- QZVHYFUVMQIGGM-UHFFFAOYSA-N
- LogP
- 5.01
- CAS DataBase Reference
- 18794-77-9(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
H413May cause long lasting harmful effects to aquatic life
- Precautionary statements
-
P273Avoid release to the environment.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 693405
- Product name
- 2-Hexylthiophene
- Purity
- 97%
- Packaging
- 5g
- Price
- $88.54
- Updated
- 2025/07/31
- Product number
- H1350
- Product name
- 2-Hexylthiophene
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $62
- Updated
- 2025/07/31
- Product number
- H1350
- Product name
- 2-Hexylthiophene
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $209
- Updated
- 2025/07/31
- Product number
- B412848
- Product name
- 2-Hexylthiophene
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- W4053
- Product name
- 2-Hexylthiophene
- Packaging
- 1g
- Price
- $14
- Updated
- 2021/12/16
2-Hexylthiophene Chemical Properties,Usage,Production
Chemical Properties
Light yellow liquid
Chemical Properties
Colorless to pale yellow liquid; meat-like aroma
Occurrence
Reported found in beef, cranberry, mushroom and turkey.
Uses
2-n-Hexylthiophene is used as a important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals.
Definition
ChEBI: 2-Hexylthiophene is a heteroarene.
Aroma threshold values
High strength odor, sulfurous type; recommend smelling in a 0.10% solution or less
Synthesis
188290-36-0
111-25-1
18794-77-9
To a solution of thiophene (5.0 g, 60 mmol) in tetrahydrofuran (THF, 50 mL) was added slowly and dropwise n-butyllithium (n-BuLi, 40.6 mL, 65 mmol, 1.6 M hexane solution) at -78 °C and under nitrogen protection. The reaction mixture was stirred at -78 °C for 1 hour. Subsequently, 1-bromohexane (10.7 g, 65 mmol) was slowly added to the reaction system and the reaction mixture was gradually warmed to room temperature and stirring was continued for 12 hours. After completion of the reaction, the reaction was quenched with water and the product was extracted with ether. The organic phase was washed sequentially with water and saturated saline, dried over anhydrous magnesium sulfate (MgSO4) and concentrated under reduced pressure. The crude product was purified by rapid column chromatography on silica gel, using hexane as eluent, to give 2-hexylthiophene (2a) as a colorless liquid. Yield: 8.3 g (82% yield). The product was characterized as follows: IR (KBr, cm-1): 3071 (sp2 C-H stretching vibration), 2921-2854 (sp3 C-H stretching vibration), 1470 (C=C stretching vibration); 1H NMR (300 MHz, CDCl3, δ/ppm): 7.08 (d, 1H, J=4.8Hz), 6.88 (dd, 1H J=4.8Hz), 6.69 (d, 1H, J=3.3Hz), 2.81 (t, 2H, J=7.7Hz), 1.68-1.61 (m, 2H), 1.34-1.26 (m, 6H), 1.02-0.98 (t, 3H, J=1.8Hz); EIMS m/z (relative abundance): 168 (100, M+).
References
[1] Organic Letters, 2002, vol. 4, # 12, p. 2067 - 2070
[2] Journal of Organic Chemistry, 2009, vol. 74, # 7, p. 2718 - 2725
[3] Inorganic Chemistry, 2018, vol. 57, # 3, p. 1527 - 1534
[4] Chinese Chemical Letters, 2011, vol. 22, # 7, p. 819 - 822
[5] Bulletin of the Korean Chemical Society, 2012, vol. 33, # 11, p. 3810 - 3816
2-Hexylthiophene Preparation Products And Raw materials
Raw materials
Preparation Products
2-Hexylthiophene Suppliers
- Tel
- --
- Fax
- --
- chiron@chiron.no
- Country
- Norway
- ProdList
- 2801
- Advantage
- 72
View Lastest Price from 2-Hexylthiophene manufacturers
- Product
- 2-Hexylthiophene 18794-77-9
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5tons
- Release date
- 2024-12-04
- Product
- 2-Hexylthiophene 18794-77-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10ton
- Release date
- 2024-07-22
- Product
- 2-Hexylthiophene 18794-77-9
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-30