L-GLUTAMINE-AMIDE-15N Property

Melting point:

185 °C (dec.)(lit.)

storage temp. 

Room Temperature

solubility 

Aqueous Acid (Very Slightly), Water (Slightly)

form 

Solid

color 

White to Off-White

optical activity

[α]25/D +33.0°, c = 2 in 5 M HCl

Safety

WGK Germany 

3

Hazard and Precautionary Statements (GHS)

L-GLUTAMINE-AMIDE-15N Chemical Properties,Usage,Production

Uses

Labelled L-Glutamine (G597000). L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.

Uses

(L-Glutamine-amide-15N) Labelled Gluamine. L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.

General Description

L-Glutamine is a branched chain, non-essential amino acid. It is one of the most abundant amino acid found in central nervous system (CNS), plasma and human skeletal muscle.(2) L- Glutamine is synthesized by transamination of glutamate catalyzed by glutamine synthetase.

Biochem/physiol Actions

L-Glutamine, a source of nitrogen, mainly contributes to the synthesis of proteins, peptides, purine, pyrimidine, nucleotides, nucleic acids and major precursor of neurotransmitter. It acts as a fuel for the proliferation of lymphocytes and macrophages of immune system, for intestinal tissue to maintain gut integrity and for insulin production.(4)(3) L-Glutamine is released by skeletal muscle during stress conditions.