DESMETHYLDOXEPIN Property

Melting point:

63-65℃

Boiling point:

408.57°C (rough estimate)

Density 

1.0629 (rough estimate)

refractive index 

1.5100 (estimate)

Flash point:

9℃

storage temp. 

-20°C

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

pKa 9.75(I=0.00 t=25.0) (Uncertain)

form 

Solid

color 

White

Water Solubility 

104.8mg/L(25 ºC)

EPA Substance Registry System

1-Propanamine, 3-dibenz[b,e]oxepin-11(6H)-ylidene-N-methyl- (1225-56-5)

Safety

Hazard Codes 

F,T

Risk Statements 

11-23/24/25-39/23/24/25

Safety Statements 

7-16-36/37-45

RIDADR 

UN1230 - class 3 - PG 2 - Methanol, solution

WGK Germany 

2

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P311Call a POISON CENTER or doctor/physician.

DESMETHYLDOXEPIN Chemical Properties,Usage,Production

Uses

Desmethyldoxepin solution may be used as an internal standard in the high performance liquid chromatographic (HPLC) determination of bupivacaine in samples of human serum.

Definition

ChEBI: (E)-desmethyldoxepin is the (E)-isomer of desmethyldoxepin.

General Description

Desmethyldoxpein is the primary urinary metabolite of doxepin, a tricyclic antidepressant used for the treatment of sleep maintenance and sold under trade names such as Silenor^? and Aponal. This analytical reference standard is suited for use in LC/MS or GC/MS methods for urine drug testing, clinical toxicology, and forensic analysis applications.