ChemicalBook > CAS DataBase List > CAPECITABINE-D11

CAPECITABINE-D11

Product Name: CAPECITABINE-D11
CAS No.: 1132662-08-8
Chemical Name: CAPECITABINE-D11
Synonyms: Xeloda-d11;Captabin-d11;Capiibine-d11;Ro 09-1978-d11;Capecytabine-d11;Capecitibine-d11;CAPECITABINE-D11;D11-Capecitabine;Ro 09-1978/000-d11;[2H11]-Capecitabine
CBNumber: CB8457758
Molecular Formula: C15H13D11FN3O6
Formula Weight: 372.43
MOL File: Mol file

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CAPECITABINE-D11 Property

Melting point:: 45-50°C
storage temp.: -20°C Freezer, Under Inert Atmosphere
solubility: DMSO (Slightly), Methanol (Slightly, Heated)
form: Solid
color: Off-White to Pale Yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H341Suspected of causing genetic defects

H350May cause cancer

H360May damage fertility or the unborn child

H402Harmful to aquatic life

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 10010681
Product name: Capecitabine-d11
Purity: ≥99% deuterated forms (d1-d11)
Packaging: 1mg
Price: $299
Updated: 2024/03/01

Cayman Chemical

Product number: 10010681
Product name: Capecitabine-d11
Purity: ≥99% deuterated forms (d1-d11)
Packaging: 5mg
Price: $595
Updated: 2024/03/01

TRC

Product number: C175652
Product name: Capecitabine-d11
Packaging: 5mg
Price: $350
Updated: 2021/12/16

Usbiological

Product number: C1077-05A
Product name: Capecitabine-d11
Packaging: 1mg
Price: $425
Updated: 2021/12/16

TRC

Product number: C175652
Product name: Capecitabine-d11
Packaging: 10mg
Price: $580
Updated: 2021/12/16

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CAPECITABINE-D11 Chemical Properties,Usage,Production

Description

Capecitabine-d₁₁ is intended for use as an internal standard for the quantification of capecitabine by GC- or LC-MS. Capecitabine is a prodrug form of 5-fluorouracil (5-FU). It is converted to 5-FU via several enzymatic steps beginning in the liver and ending with conversion in tumor tissue by thymidine phosphorylase, an enzyme that is more concentrated in tumor tissue compared with normal tissue. Capecitabine is cytotoxic only at high concentrations in Scaber, SIHA, and MKN45 cells (IC₅₀s = 97, 578, and 994 μM, respectively) and is inactive in a variety of cancer cell lines, including COLO 205, HCT116, and MCF-7 cells (IC₅₀s = >1,000 μM).

Chemical Properties

Off-White Powder

Uses

Capecitabine D11 is an isotopically labelled antineoplastic agent. A prodrug of Doxifluridine.;Labeled Capecitabine, intended for use as an internal standard for the quantification of Capecitabine by GC- or LC-mass spectrometry.

Uses

An isotopically labelled antineoplastic agent. A prodrug of Doxifluridine (D556750).

References

[1] M MIWA. Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue[J]. European Journal of Cancer, 1998, 34 8: Pages 1274-1281. DOI: 10.1016/s0959-8049(98)00058-6

CAPECITABINE-D11 Preparation Products And Raw materials

Raw materials

Preparation Products

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1132662-08-8, CAPECITABINE-D11Related Search:

Capecitabine

5'-Deoxy-5-fluoro-N-[(pentyl-d11-oxy)carbonyl]cytidine

Capecitibine-d11

Capecytabine-d11

Capiibine-d11

Captabin-d11

Ro 09-1978/000-d11

Ro 09-1978-d11

Xeloda-d11

[1-(5-Deoxy-α-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyriMidinyl]carbaMic Acid Pentyl-11 Ester

5'-DEOXY-5-FLUORO-N-[(PENTYLOXY)CARBONYL]CYTIDINE-D11

CAPECITABINE-D11

[2H11]-Capecitabine

Capecitabine D11Q: What is Capecitabine D11 Q: What is the CAS Number of Capecitabine D11 Q: What is the storage condition of Capecitabine D11 Q: What are the applications of Capecitabine D11

2’-O-(5’-Deoxy-?-D-ribofuranosyl) Capecitabine-d11

D11-Capecitabine

1132662-08-8

C15H11D11FN3O6

Isotope Labelled Compounds

Bases & Related Reagents

Intermediates & Fine Chemicals

Isotope Labeled Compounds

Nucleotides

Pharmaceuticals