RARECHEM AL BI 1318
- Product Name
- RARECHEM AL BI 1318
- CAS No.
- 59937-01-8
- Chemical Name
- RARECHEM AL BI 1318
- Synonyms
- RARECHEM AL BI 1318;ethyl 2-phenylthiazole-4-carboxylate;2-PHENYL-THIAZOLE-4-CARBOXYLIC ACID ETHYL ESTER;4-THIAZOLECARBOXYLIC ACID, 2-PHENYL-, ETHYL ESTER
- CBNumber
- CB8462594
- Molecular Formula
- C12H11NO2S
- Formula Weight
- 233.29
- MOL File
- 59937-01-8.mol
RARECHEM AL BI 1318 Property
- Melting point:
- 47 °C
- Boiling point:
- 365℃
- Density
- 1.216
- Flash point:
- 175℃
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 0.09±0.10(Predicted)
N-Bromosuccinimide Price
- Product number
- P000167550
- Product name
- Ethyl 2-phenylthiazole-4-carboxylate
- Purity
- 97%
- Packaging
- 1g
- Price
- $70
- Updated
- 2021/12/16
- Product number
- Z3167
- Product name
- Ethyl2-phenylthiazole-4-carboxylate
- Packaging
- 1g
- Price
- $171
- Updated
- 2021/12/16
- Product number
- P000167550
- Product name
- Ethyl 2-phenylthiazole-4-carboxylate
- Purity
- 97%
- Packaging
- 5g
- Price
- $224
- Updated
- 2021/12/16
- Product number
- 113991
- Product name
- Ethyl 2-phenyl-1,3-thiazole-4-carboxylate
- Purity
- 97%
- Packaging
- 1g
- Price
- $260
- Updated
- 2021/12/16
- Product number
- P000167550
- Product name
- Ethyl 2-phenylthiazole-4-carboxylate
- Purity
- 97%
- Packaging
- 10g
- Price
- $381
- Updated
- 2021/12/16
RARECHEM AL BI 1318 Chemical Properties,Usage,Production
Synthesis
70454-09-0
59937-01-8
GENERAL METHOD: 4-carboxythiazoline or 4-carboxyoxazoline (0.5 mmol) was dissolved in anhydrous DMF (1 mL), molecular sieves (4 ? , 100% wt) and copper(II) acetate (9.1 mg, 0.05 mmol). The reaction mixture was stirred at 120 °C for 10 to 24 h under an oxygen atmosphere (using an O2 balloon). After completion of the reaction, the reaction mixture was diluted with ethyl acetate, the organic layer was washed sequentially with water and brine, dried with anhydrous sodium sulfate, filtered, and the filtrate was concentrated under reduced pressure. The concentrated residue was purified by silica gel fast column chromatography to obtain the target product 4-carboxythiazole or 4-carboxyoxazole.
References
[1] Tetrahedron, 2011, vol. 67, # 38, p. 7406 - 7411
RARECHEM AL BI 1318 Preparation Products And Raw materials
Raw materials
Preparation Products
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