ChemicalBook > CAS DataBase List > PrDiAzK
PrDiAzK
- Product Name
- PrDiAzK
- CAS No.
- 2231405-64-2
- Chemical Name
- PrDiAzK
- Synonyms
- PrDiAzK;bifunctional Cross-Linking-Amino-Acid / PrDiAzK;L-Lysine, N6-[[[3-[(2-propyn-1-yloxy)methyl]-3H-diazirin-3-yl]methoxy]carbonyl]-
- CBNumber
- CB84656148
- Molecular Formula
- C13H20N4O5
- Formula Weight
- 312.32
- MOL File
- 2231405-64-2.mol
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PrDiAzK Property
- Density
- 1.33±0.1 g/cm3(Predicted)
- pka
- 2.53±0.24(Predicted)
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PrDiAzK Chemical Properties,Usage,Production
Uses
PrDiAzK is a bifunctional amino acid. PrDiAzK can be site-selectively incorporated into proteins in both bacterial and mammalian cell culture. PrDiAzK can be used for proteome-wide incorporation via stochastic orthogonal recoding of translation (SORT)[1]. PrDiAzK is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
References
[1] Hoffmann JE, et L. A Bifunctional Noncanonical Amino Acid: Synthesis, Expression, and Residue-Specific Proteome-wide Incorporation. Biochemistry. 2018;57(31):4747-4752. DOI:10.1021/acs.biochem.8b00397
PrDiAzK Preparation Products And Raw materials
Raw materials
Preparation Products
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