N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite

Product Name: N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite
CAS No.: 142808-44-4
Chemical Name: N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite
Synonyms: Gemcitabine 3'-CE Phosphoramidite;Gemcitabine 3'-CE Phosphoramidite;N4-Bz-DMT-2',2'-difluoro-dC-CE-Phosphoramidite;DMTr-2',2'-diFluoro-dC(Bz)-3'-CE-Phosphoramidite;DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite;DMTr-2’,2’-di fluoro-dC(Bz)-3’-CED-phosphoramidite;5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite;5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite;N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite;N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',2'-difluoro-2'-deoxycytidine
CBNumber: CB84659422
Molecular Formula: C46H50F2N5O8P
Formula Weight: 869.89
MOL File: 142808-44-4.mol

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N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite Property

pka: 8.38±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: PB158887
Product name: N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine 3'-CE phosphoramidite
Packaging: 5mg
Price: $50
Updated: 2021/12/16

Biosynth Carbosynth

Product number: PB158887
Product name: N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine 3'-CE phosphoramidite
Packaging: 10mg
Price: $80
Updated: 2021/12/16

Biosynth Carbosynth

Product number: PB158887
Product name: N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine 3'-CE phosphoramidite
Packaging: 25mg
Price: $125
Updated: 2021/12/16

Biosynth Carbosynth

Product number: PB158887
Product name: N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine 3'-CE phosphoramidite
Packaging: 50mg
Price: $190
Updated: 2021/12/16

Biosynth Carbosynth

Product number: PB158887
Product name: N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine 3'-CE phosphoramidite
Packaging: 100mg
Price: $250
Updated: 2021/12/16

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N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite Chemical Properties,Usage,Production

Uses

N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis

1.Dissolve 5'-Dimethoxytrityl-N 4-benzoyl-2',2'-difluoro-2'-deoxycytidine (1 equiv., 0.4 mmol, 270 mg)in anhydrous acetonitrile (6 ml).
2.Add 0.5 M solution of ethylothiotetrazole (1.6 equiv., 0.65 mM, 1.3 ml) in anhydrous acetonitrile and 2-cyanoethyl-bis-(N,N'-diisopropropyl)phosphoramidite (1.43 equiv., 0.57 mmol, 0.2 ml) to the above solution.
3.Stir the reaction mixture at room temperature for 1 h to obtain product.

N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite Suppliers

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142808-44-4, N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramiditeRelated Search:

N-Benzoyl-2-deoxy-5-O-DMT-2',2'-difluorocytidine 3-CE phosphoramidite

N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',2'-difluoro-2'-deoxycytidine

5'-O-DMT-N4-Benzoyl-2',2'-difluoro-2'-deoxycytidine 3'-CE phosphoramidite

N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine 3'-CE phosphoramidite

Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2',2'-difluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

DMTr-2’,2’-di fluoro-dC(Bz)-3’-CED-phosphoramidite

N4-Benzoyl-5’-O-(4,4’-dimethoxy trityl) -2’,2’-difluoro-2’-deoxycytidine 3’-O-[(2-cyanoethyl) (N,N-diisopropyl)]-phosphoramidite

N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',2'-difluoro-2'-deoxycytidine-3'-cyanoethyl Phosphoramidite

N4-Bz-DMT-2',2'-difluoro-dC-CE-Phosphoramidite

5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite

(2R,3R,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4,4-difluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

Gemcitabine 3'-CE Phosphoramidite

DMTr-2',2'-diFluoro-dC(Bz)-3'-CE-Phosphoramidite

N4-Benzoyl-2'-deoxy-5'-O-DMTr-2', 2'-difluorocytidine 3'-cyanoethyl phosphoramidite

N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',2'-difluoro-2'-deoxycytidine-3'-cyanoethylPhosphoramidite

DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite

Gemcitabine 3'-CE Phosphoramidite

5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite

142808-44-4

C46H50F2N5O8P

Other

Phosphoramidite