Biotin-Teg-Nh2 Tfa

Product Name: Biotin-Teg-Nh2 Tfa
CAS No.: 1334172-59-6
Chemical Name: Biotin-Teg-Nh2 Tfa
Synonyms: CAS_1334172-59-6;Biotin-Teg-Nh2 Tfa;Biotin-dPEG??-NH?+TFA-;Biotin-C1-PEG3-C3-amine TFA;Biotin-dPEG??-NH?+TFA- (QBD-10193);1H-Thieno[3,4-d]imidazol-2(3H)-one, 4-[8-[2-[2-(3-aminopropoxy)ethoxy]ethoxy]-5-oxooctyl]tetrahydro-, (3aS,4S,6aR)-, 2,2,2-trifluoroacetate (1:1)
CBNumber: CB84660886
Molecular Formula: C20H38N4O5S.C2HF3O2
Formula Weight: 545.62
MOL File: 1334172-59-6.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

dPEG

Product number: 10193
Product name: Biotin-dPEG®₃-NH₃+TFA-
Packaging: 100mg
Price: $100
Updated: 2021/12/16

AK Scientific

Product number: 6190AH
Product name: Biotin-Teg-Nh2Tfa
Packaging: 25mg
Price: $198
Updated: 2021/12/16

Iris Biotech GmbH

Product number: PEG2110
Product name: Biotin-dPEG™(3)-NH2*TFA
Packaging: 100mg
Price: $270
Updated: 2021/12/16

AK Scientific

Product number: 6190AH
Product name: Biotin-Teg-Nh2Tfa
Packaging: 250mg
Price: $846
Updated: 2021/12/16

Iris Biotech GmbH

Product number: PEG2110
Product name: Biotin-dPEG™(3)-NH2*TFA
Packaging: 1g
Price: $1296
Updated: 2021/12/16

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Biotin-Teg-Nh2 Tfa Chemical Properties,Usage,Production

Uses

Biotin-C1-PEG3-C3-amine (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Biological Activity

Biotin-C1-PEG3-C3-amine (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Biotin-Teg-Nh2 Tfa Preparation Products And Raw materials

Raw materials

Preparation Products

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Biotin-Teg-Nh2 Tfa Suppliers

China 21 India 1 United States 2 Global 24

Borenpharm Co., Ltd

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Henan Alfachem Co.,Ltd.

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Jiangsu aikang biomedical research and development co., LTD

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TargetMol Chemicals Inc.

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Wuhan Borenpharm Co., Ltd

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Shaanxi borno biotechnology co., LTD

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Zhengzhou anmousse chemical products co. LTD

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Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

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1334172-59-6, Biotin-Teg-Nh2 TfaRelated Search:

Biotin-Teg-Nh2 Tfa

1H-Thieno[3,4-d]imidazol-2(3H)-one, 4-[8-[2-[2-(3-aminopropoxy)ethoxy]ethoxy]-5-oxooctyl]tetrahydro-, (3aS,4S,6aR)-, 2,2,2-trifluoroacetate (1:1)

CAS_1334172-59-6

Biotin-C1-PEG3-C3-amine TFA

Biotin-dPEG??-NH?+TFA-

Biotin-dPEG??-NH?+TFA- (QBD-10193)

1334172-59-6