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ABC34

Product Name
ABC34
CAS No.
1831135-56-8
Chemical Name
ABC34
Synonyms
ABC34;4-(4-methoxyphenyl)-1-piperazinecarboxylicacid,hexahydro-1,3-dioxo-7-[(4-phenoxyphenyl)methyl]imidazo[1,5-a]pyrazin-2-ylester;1-Piperazinecarboxylic acid, 4-(4-methoxyphenyl)-, hexahydro-1,3-dioxo-7-[(4-phenoxyphenyl)methyl]imidazo[1,5-a]pyrazin-2-yl ester
CBNumber
CB84665861
Molecular Formula
C31H33N5O6
Formula Weight
571.62
MOL File
1831135-56-8.mol
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ABC34 Property

Boiling point:
694.7±65.0 °C(Predicted)
Density 
1.41±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 20 mg/mL; DMF:PBS (pH 7.2)(1:3): 0.25 mg/mL; DMSO: 10 mg/mL
form 
A crystalline solid
pka
7.92±0.20(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19385
Product name
ABC34
Purity
≥98%
Packaging
500μg
Price
$97
Updated
2024/03/01
Cayman Chemical
Product number
19385
Product name
ABC34
Purity
≥98%
Packaging
1mg
Price
$184
Updated
2024/03/01
Cayman Chemical
Product number
19385
Product name
ABC34
Purity
≥98%
Packaging
5mg
Price
$862
Updated
2024/03/01
AK Scientific
Product number
3133EF
Product name
[1,3-Dioxo-7-[(4-phenoxyphenyl)methyl]-5,6,8,8a-tetrahydroimidazo[1,5-a]pyrazin-2-yl]4-(4-methoxyphenyl)piperazine-1-carboxylate
Packaging
5mg
Price
$1058
Updated
2021/12/16
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ABC34 Chemical Properties,Usage,Production

Description

ABC34 is an inactive control probe for JJH260 , the inhibitor of androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs). ABC34 demonstrates an IC50 value greater than 25 μM for the inhibition of 9-PAHSA but is more potent in blocking the serine hydrolase ABHD6 and the palmitoyl-protein hydrolase PPT1, which are both off-targets of JJH260.

Uses

ABC34 is an inactive control compound of JJH260. ABC34 does not inhibit the fluorophosphonate reactivity or fatty acid esters of hydroxy fatty acid (FAHFA) hydrolysis activity of AIG1. ABC34 can inhibit both ABHD6 and PPT122[1].

References

[1] William H Parsons, et al. AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs. Nat Chem Biol. 2016 May;12(5):367-372. DOI:10.1038/nchembio.2051

ABC34 Preparation Products And Raw materials

Raw materials

Preparation Products

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ABC34 Suppliers

BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
Shanghai Beckham Medical Technology Co., Ltd
Tel
13816613772
Fax
QQ: 12922499
Email
huahero21@sina.com
Country
China
ProdList
2391
Advantage
55
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11973
Advantage
58
Cayman Chemical Company
Tel
800-364-9897
Email
sales@caymanchem.com
Country
China
ProdList
6838
Advantage
58
Aoki Biotechnology (Shenzhen) Co., Ltd.
Tel
18566777408
Country
CHINA
ProdList
156
Advantage
58

1831135-56-8, ABC34Related Search:


  • ABC34
  • 1-Piperazinecarboxylic acid, 4-(4-methoxyphenyl)-, hexahydro-1,3-dioxo-7-[(4-phenoxyphenyl)methyl]imidazo[1,5-a]pyrazin-2-yl ester
  • 4-(4-methoxyphenyl)-1-piperazinecarboxylicacid,hexahydro-1,3-dioxo-7-[(4-phenoxyphenyl)methyl]imidazo[1,5-a]pyrazin-2-ylester
  • 1831135-56-8