ChemicalBook > CAS DataBase List > CCG-232601
CCG-232601
- Product Name
- CCG-232601
- CAS No.
- 1922099-21-5
- Chemical Name
- CCG-232601
- Synonyms
- CCG-232601;CCG-232601 (CCG232601);N-(4-chlorophenyl)-5,5-difluoro-1-[3-(4-pyridinyl)benzoyl]-3-piperidinecarboxamide;3-Piperidinecarboxamide, N-(4-chlorophenyl)-5,5-difluoro-1-[3-(4-pyridinyl)benzoyl]-
- CBNumber
- CB84665922
- Molecular Formula
- C24H20ClF2N3O2
- Formula Weight
- 455.88
- MOL File
- 1922099-21-5.mol
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CCG-232601 Property
- Boiling point:
- 683.1±55.0 °C(Predicted)
- Density
- 1.39±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
- form
- A crystalline solid
- pka
- 13.69±0.70(Predicted)
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 24382
- Product name
- CCG-232601
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $109
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 24382
- Product name
- CCG-232601
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $481
- Updated
- 2024/03/01
AK Scientific
- Product number
- 5832EG
- Product name
- N-(4-Chlorophenyl)-5,5-difluoro-1-(3-pyridin-4-ylbenzoyl)piperidine-3-carboxamide
- Packaging
- 5mg
- Price
- $617
- Updated
- 2021/12/16
Axon Medchem
- Product number
- Axon2753
- Product name
- CCG232601
- Purity
- 99%
- Packaging
- 5mg
- Price
- $176
- Updated
- 2021/12/16
AK Scientific
- Product number
- 5832EG
- Product name
- N-(4-Chlorophenyl)-5,5-difluoro-1-(3-pyridin-4-ylbenzoyl)piperidine-3-carboxamide
- Packaging
- 1mg
- Price
- $214
- Updated
- 2021/12/16
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CCG-232601 Chemical Properties,Usage,Production
Description
CCG-232601 is an inhibitor of the Rho/MRTF/SRF transcriptional pathway and a derivative of CCG-203971 . CCG-232601 inhibits MRTF-dependent transcription in HEK293T cells (IC50 = 0.55 μM in a luciferase reporter assay). It also reduces expression of α-smooth muscle actin (α-SMA) in TGF-β-stimulated human dermal fibroblasts to 31% of control when used at a concentration of 10 μM. CCG-232601 (50 mg/kg) inhibits increases in dermal thickness and hydroxyproline content in a mouse model of dermal fibrosis induced by bleomycin .
CCG-232601 Preparation Products And Raw materials
Raw materials
Preparation Products
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CCG-232601 Suppliers
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
- Country
- United States
- ProdList
- 14055
- Advantage
- 65
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32161
- Advantage
- 58
- Tel
- --
- Fax
- --
- cayman@caymanchem.com
- Country
- United States
- ProdList
- 6213
- Advantage
- 81
- Tel
- --
- Fax
- --
- info@axonmedchem.com
- Country
- United States
- ProdList
- 763
- Advantage
- 58