Fluo-3FF (potassium salt)
- Product Name
- Fluo-3FF (potassium salt)
- CAS No.
- 348079-14-1
- Chemical Name
- Fluo-3FF (potassium salt)
- Synonyms
- Fluo-3FF (potassium salt);Potassium 2,2'-((2-(2-(6-(bis(carboxylatomethyl)amino)-2,3-difluorophenoxy)ethoxy)-4-(2,7-dichloro-6-oxido-3-oxo-3H-xanthen-9-yl)phenyl)azanediyl)diacetate;Pentapotassium, 2-[2-[2-[6-[bis(carboxylatomethyl)amino]-2,3-difluorophenoxy]ethoxy]-N-(carboxylatomethyl)-4-(2,7-dichloro-3-oxido-6 -oxoxanthen-9-yl)anilino]acetate;N-[2-[2-[2-[bis(carboxymethyl)amino]-5-(2,7-dichloro-6-hydroxy-3-oxo-3H-xanthen-9-yl)phenoxy]ethoxy]-3,4-difluorophenyl]-N-(carboxymethyl)-glycine,pentapotassiumsalt
- CBNumber
- CB84665962
- Molecular Formula
- C35H27Cl2F2KN2O13
- Formula Weight
- 831.6
- MOL File
- 348079-14-1.mol
Fluo-3FF (potassium salt) Property
- storage temp.
- Store at -20°C
- solubility
- Water: soluble
- form
- A solid
N-Bromosuccinimide Price
- Product number
- 20406
- Product name
- Fluo-3FF (potassium salt)
- Purity
- ≥90%
- Packaging
- 1mg
- Price
- $384
- Updated
- 2024/03/01
- Product number
- 3134EL
- Product name
- Pentapotassium;2-[2-[2-[6-[bis(carboxylatomethyl)amino]-2,3-difluorophenoxy]ethoxy]-N-(carboxylatomethyl)-4-(2,7-dichloro-3-oxido-6-oxoxanthen-9-yl)anilino]acetate
- Packaging
- 1mg
- Price
- $525
- Updated
- 2021/12/16
Fluo-3FF (potassium salt) Chemical Properties,Usage,Production
Description
Fluo-3FF is a fluorescent calcium indicator. It is a di-fluorinated analog of Fluo-3 (Item Nos. 20402 | 20403 | 20404) that displays about a 100-fold lower affinity than Fluo-3 for calcium (Kds = 42 and 0.4 μM, respectively). Low affinity calcium indicators are particularly useful for studying compartments with high concentrations of calcium, such as endoplasmic reticulum, where high affinity dyes will be insensitive to luminal fluctuations. Fluo-3FF has excitation/emission maxima of approximately 506 and 526 nm, respectively.
Uses
Fluo-3FF pentapotassium is a cell-permeable acetoxy-methyl ester of Fluo-3FF, a fluorescent calcium indicator. Fluo-3FF is a di-fluorinated analog of Fluo-3 with a 100-fold lower affinity than Fluo-3 for calcium (Kds=42 and 0.4 M, respectively). For its low affinity, Fluo-3FF is used for studying compartments with high concentrations of calcium, such as endoplasmic reticulum, where high affinity dyes will be insensitive to luminal fluctuations.
References
[1] GAVRIEL DAVID Ellen F B John N Barrett. Stimulation-induced changes in [ca2+] in lizard motor nerve terminals[J]. Journal of Physiology-London, 2004, 504 1: 83-96. DOI: 10.1111/j.1469-7793.1997.083bf.x
Fluo-3FF (potassium salt) Preparation Products And Raw materials
Raw materials
Preparation Products
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