N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone
- Product Name
- N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone
- CAS No.
- 273734-65-9
- Chemical Name
- N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone
- Synonyms
- (S)-N-3-hydroxy-(7Z)-tetradecenoyl-homoserine lactone;N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone;3-hydroxy-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-7Z-tetradecenamide;7-Tetradecenamide, 3-hydroxy-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-, (7Z)-
- CBNumber
- CB84666611
- Molecular Formula
- C18H31NO4
- Formula Weight
- 325.44
- MOL File
- 273734-65-9.mol
N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone Property
- Boiling point:
- 569.7±50.0 °C(Predicted)
- Density
- 1.06±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
- pka
- 14.22±0.20(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
H336May cause drowsiness or dizziness
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 9002939
- Product name
- N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
- Product number
- 9002939
- Product name
- N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $193
- Updated
- 2024/03/01
- Product number
- 9002939
- Product name
- N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $341
- Updated
- 2024/03/01
- Product number
- 9002939
- Product name
- N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $745
- Updated
- 2024/03/01
- Product number
- 8650CN
- Product name
- N-(3-Hydroxy-7-cis-tetradecenoyl)homoserinelactone
- Packaging
- 25mg
- Price
- $927
- Updated
- 2021/12/16
N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone Chemical Properties,Usage,Production
Description
N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone is a long-chain N-acyl-homoserine lactone (AHL) produced by some Gram-negative bacteria and is involved in quorum sensing.1 Quorum sensing enables bacteria to change gene expression based on cues from nearby bacteria and from eukaryotic hosts about nutrients, environmental conditions, or threats.2 Due to the benefit of quorum sensing for bacterial survival, quorum sensing molecules are potential targets for controlling bacterial infections.3 In mouse and human leukocyte immunoassays using LPS-stimulated macrophages, N-(3-hydroxy-7-cis tetradecenoyl)-L-homoserine lactone did not have an effect on cytokine or antibody production.4
Definition
ChEBI: N-(3-Hydroxy-7-cis-tetradecenoyl)homoserine lactone is a N-acyl-amino acid.
References
1. Laue, B.E., Jiang, Y., Chhabra, S.R., et al. The biocontrol strain Pseudomonas fluorescens F113 produces the Rhizobium small bacteriocin, N-
2. Williams, P. Quorum sensing, communication and cross-
3. Meng, L.J., and Sj?vall, J. Method for combined analysis of profiles of conjugated progesterone metabolites and bile acids in serum and urine of pregnant women J. Chromatogr. B Biomed. Sci. Appl. 688(1),11-26(1997).
4. Telford, G., Wheeler, D., Williams, P., et al. The Pseudomonas aeruginosa quorum-
N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone Preparation Products And Raw materials
Raw materials
Preparation Products
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