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Padanamide A

Product Name
Padanamide A
CAS No.
1314881-80-5
Chemical Name
Padanamide A
Synonyms
Padanamide A;(S)-N-((2S,3S,4S)-5-(((S)-1-carbamoyl-2-oxopyrrolidin-3-yl)amino)-3-hydroxy-4-methyl-5-oxo-1-phenylpentan-2-yl)-2-((2R,3R)-3-hydroxy-2-(2-methoxyacetamido)-4-methylpentanoyl)hexahydropyridazine-3-carboxamide
CBNumber
CB84666767
Molecular Formula
C31H47N7O9
Formula Weight
661.74638
MOL File
1314881-80-5.mol
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Padanamide A Property

Density 
1.34±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form 
A solid
pka
13.24±0.46(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
25085
Product name
Padanamide A
Purity
≥95%
Packaging
1mg
Price
$153
Updated
2024/03/01
Cayman Chemical
Product number
25085
Product name
Padanamide A
Purity
≥95%
Packaging
5mg
Price
$533
Updated
2024/03/01
AK Scientific
Product number
3522DL
Product name
(3S)-N-[(2S,3S,4S)-5-[[(3S)-1-Carbamoyl-2-oxopyrrolidin-3-yl]amino]-3-hydroxy-4-methyl-5-oxo-1-phenylpentan-2-yl]-2-[(2R,3R)-3-hydroxy-2-[(2-methoxyacetyl)amino]-4-methylpentanoyl]diazinane-3-carboxamide
Packaging
1mg
Price
$268
Updated
2021/12/16
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Padanamide A Chemical Properties,Usage,Production

Description

Padanamide A is a bacterial metabolite originally isolated from a marine Streptomyces species.1 It is active against five strains of P. falciparum (EC50s = 160-340 nM), is not cytotoxic to HEK293 or HepG2 human cell lines, but is cytotoxic to Jurkat T lymphocytes with an IC50 value of approximately 60 μg/ml.2,3

References

1. Nam, S.J., Kauffman, C.A., Jensen, P.R., et al. Isolation and characterization of actinoramides A-C, highly modified peptides from a marine Streptomyces sp Tetrahedron 67(35),6707-6712(2011).
2. Cheng, K.-C., Cao, S., Raveh, A., et al. Actinoramide A identified as a potent antimalarial from titration-based screening of marine natural product extracts J. Nat. Prod. 78(10),2411-2422(2015).
3. Williams, D.E., Dalisay, D.S., Patrick, B.O., et al. Padanamides A and B, highly modified linear tetrapeptides produced in culture by a Streptomyces sp. isolated from a marine sediment Org. Lett. 13(15),3936-3939(2011).

Padanamide A Preparation Products And Raw materials

Raw materials

Preparation Products

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Padanamide A Suppliers

China 4 United States 2 Global 6
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6870
Advantage
58
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19743
Advantage
58
Meng Cheng Technology (Shanghai) Co., LTD
Tel
400-820-6829
Email
sales@mitachieve.com
Country
China
ProdList
8864
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
8740
Advantage
58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.com
Country
China
ProdList
24246
Advantage
58

1314881-80-5, Padanamide ARelated Search:


  • Padanamide A
  • (S)-N-((2S,3S,4S)-5-(((S)-1-carbamoyl-2-oxopyrrolidin-3-yl)amino)-3-hydroxy-4-methyl-5-oxo-1-phenylpentan-2-yl)-2-((2R,3R)-3-hydroxy-2-(2-methoxyacetamido)-4-methylpentanoyl)hexahydropyridazine-3-carboxamide
  • 1314881-80-5