ChemicalBook > CAS DataBase List > Petromurin C
Petromurin C
- Product Name
- Petromurin C
- CAS No.
- 194608-29-2
- Chemical Name
- Petromurin C
- Synonyms
- Petromurin C;3-[4-(1H-indol-3-yl)-2,3,5,6-tetramethoxyphenyl]-1H-indol-5-ol;1H-Indol-5-ol, 3-[4-(1H-indol-3-yl)-2,3,5,6-tetramethoxyphenyl]-
- CBNumber
- CB84666787
- Molecular Formula
- C26H24N2O5
- Formula Weight
- 444.48
- MOL File
- 194608-29-2.mol
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Petromurin C Property
- Boiling point:
- 610.7±55.0 °C(Predicted)
- Density
- 1.309±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
- form
- A solid
- pka
- 9.60±0.40(Predicted)
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 25089
- Product name
- Petromurin C
- Purity
- ≥95%
- Packaging
- 500μg
- Price
- $121
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 25089
- Product name
- Petromurin C
- Purity
- ≥95%
- Packaging
- 2.5mg
- Price
- $543
- Updated
- 2024/03/01
AK Scientific
- Product number
- 1545EA
- Product name
- CID85743767
- Packaging
- 2.5mg
- Price
- $702
- Updated
- 2021/12/16
aablocks
- Product number
- AA01EQ4L
- Product name
- 3-[4-(1H-indol-3-yl)-2,3,5,6-tetramethoxyphenyl]-1H-indol-5-ol
- Purity
- ≥95%
- Packaging
- 2.5mg
- Price
- $608
- Updated
- 2021/12/16
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Petromurin C Chemical Properties,Usage,Production
Description
Petromurin C is a bis-indolyl benzenoid fungal metabolite originally isolated from the ascostromata of P. muricatus. It is cytotoxic to NS-1 mouse myeloma cells (IC50 = 33 μg/ml) and has activity against T. foetus in vitro (IC50 = 100 μg/ml).
Uses
Petromurin C is a bisindolylbenzenoid compound isolated from the ascostromata of Petromycesmuricatus. Petromurin C induces protective autophagy and apoptosis in FLT3-ITD-positive AML[1][2].
References
[1] Mikiko Ooike, et al. Bisindolylbenzenoids from ascostromata of Petromycesmuricatus.
[2] Ha YN, et al. Petromurin C Induces Protective Autophagy and Apoptosis in FLT3-ITD-Positive AML: Synergy with Gilteritinib. Mar Drugs. 2020;18(1):57. DOI:10.3390/md18010057
Petromurin C Preparation Products And Raw materials
Raw materials
Preparation Products
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