C18 Globotriaosylceramide (d18:1/18:0)
- Product Name
- C18 Globotriaosylceramide (d18:1/18:0)
- CAS No.
- 69283-33-6
- Chemical Name
- C18 Globotriaosylceramide (d18:1/18:0)
- Synonyms
- Octadecanoyl-ceramide trihexoside;N-Octadecanoyl-ceramide trihexoside;C18 Globotriaosylceramide (d18:1/18:0);Octadecanamide, N-[(1S,2R,3E)-1-[[(O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl)oxy]methyl]-2-hydroxy-3-heptadecen-1-yl]-
- CBNumber
- CB84666974
- Molecular Formula
- C54H101NO18
- Formula Weight
- 1052.37564
- MOL File
- 69283-33-6.mol
C18 Globotriaosylceramide (d18:1/18:0) Property
- Boiling point:
- 1132.1±65.0 °C(Predicted)
- Density
- 1.22±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Chloroform:Methanol (2:1): Soluble; DMSO: Soluble; Methanol: Warmed
- form
- A solid
- pka
- 12.76±0.70(Predicted)
N-Bromosuccinimide Price
- Product number
- 24877
- Product name
- C18 Globotriaosylceramide (d18:1/18:0)
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $517
- Updated
- 2024/03/01
C18 Globotriaosylceramide (d18:1/18:0) Chemical Properties,Usage,Production
Description
C18 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from lactosylceramide . It inhibits aggregation of human neutrophils induced by phorbol 12-myristate 13-acetate (PMA; 10008014) when used at a concentration of 1 μM. C18 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raji cells and THP-1 monocytes. It accumulates in the brain, heart, kidney, liver, lung, and spleen in a mouse model of Fabry disease, a lysosomal storage disorder characterized by a deficiency in the enzyme α-galactosidase A. C18 globotriaosylceramide also accumulates in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease. [Matreya, LLC. Catalog No. 1529]
Definition
ChEBI: Alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1/18:0) is a glycotriaosylceramide having alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl as the glycotriaosyl component attached to the Cer(d18:1/18:0). It has a role as a mouse metabolite. It is functionally related to an octadecanoic acid.
C18 Globotriaosylceramide (d18:1/18:0) Preparation Products And Raw materials
Raw materials
Preparation Products
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