ML-00253764 (hydrochloride)

Product Name: ML-00253764 (hydrochloride)
CAS No.: 1706524-94-8
Chemical Name: ML-00253764 (hydrochloride)
Synonyms: ML00253764 hydrochloride,ML 00253764 hydrochloride;2-[2-[2-(5-Bromo-2-methoxyphenyl)ethyl]-3-fluorophenyl]-4,5-dihydro-2-1H-imidazole hydrochloride
CBNumber: CB84667027
Molecular Formula: C18H19BrClFN2O
Formula Weight: 413.72
MOL File: 1706524-94-8.mol

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ML-00253764 (hydrochloride) Property

storage temp.: Store at -20°C
solubility: DMF: 30mg/mL; DMF:PBS (pH 7.2) (1:20): 0.5mg/mL; DMSO: 25mg/mL; Ethanol: 1mg/mL
form: A crystalline solid
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22473
Product name: ML-00253764 (hydrochloride)
Packaging: 1mg
Price: $30
Updated: 2024/03/01

Cayman Chemical

Product number: 22473
Product name: ML-00253764 (hydrochloride)
Packaging: 5mg
Price: $141
Updated: 2024/03/01

Cayman Chemical

Product number: 22473
Product name: ML-00253764 (hydrochloride)
Packaging: 10mg
Price: $267
Updated: 2024/03/01

Cayman Chemical

Product number: 22473
Product name: ML-00253764 (hydrochloride)
Packaging: 50mg
Price: $1041
Updated: 2023/06/20

TRC

Product number: M425168
Product name: ML00253764Hydrochloride
Packaging: 1mg
Price: $115
Updated: 2021/12/16

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ML-00253764 (hydrochloride) Chemical Properties,Usage,Production

Uses

ML 00253764 Hydrochloride acts as a MC4 receptor antagonist which may be used to counteract the effects of Cachexia in cancer patients and those chronically ill which results in a loss of lean body mass.

in vivo

ML-00253764 (subcutaneous injection; 3, 10, or 30 mg/kg; once daily) shows protection against tumor-induced body weight loss upon chronic, peripheral dosing in CT-26 tumor bearing BALB/c mice^[1].ML-00253764 dissolves in polyethylene glycol 200/saline (1:10) in a volume of 10 mL/kg (For reference only)^[1].

Animal Model:	CT-26 tumor bearing BALB/c mice^[1]
Dosage:	3, 10, or 30 mg/kg
Administration:	Subcutaneous injection; 3, 10, or 30 mg/kg; once daily
Result:	Reduced tumor-induced weight loss in a mouse model.

IC 50

MC4R

storage

Store at +4°C

ML-00253764 (hydrochloride) Preparation Products And Raw materials

Raw materials

Preparation Products

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ML-00253764 (hydrochloride) Suppliers

China 10 United Kingdom 1 United States 4 Global 15

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Shanghai Tachizaki Biomedical Research Center

Tel: 18014399201
Email: sales@chemlab-tachizaki.com
Country: China
ProdList: 2742
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Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
Advantage: 58

R&D Systems, Inc

Tel: 18003437475
Fax: 1-612-656-4400
Email: rdname@qq.com
Country: China
ProdList: 6960
Advantage: 58

Cayman Chemical Company

Tel: 800-364-9897
Email: sales@caymanchem.com
Country: China
ProdList: 6838
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

1706524-94-8, ML-00253764 (hydrochloride)Related Search:

2-[2-[2-(5-Bromo-2-methoxyphenyl)ethyl]-3-fluorophenyl]-4,5-dihydro-2-1H-imidazole hydrochloride

ML00253764 hydrochloride,ML 00253764 hydrochloride

1706524-94-8