ChemicalBook > CAS DataBase List > BRD3731

BRD3731

Product Name
BRD3731
CAS No.
2056262-08-7
Chemical Name
BRD3731
Synonyms
BRD3731;(R)-BRD3731;BRD3731 (BRD-3731;5H-Pyrazolo[3,4-b]quinolin-5-one, 3-(2,2-dimethylpropyl)-1,2,4,6,7,8-hexahydro-4,7,7-trimethyl-4-phenyl-, (4R)-
CBNumber
CB84667683
Molecular Formula
C24H31N3O
Formula Weight
377.52
MOL File
2056262-08-7.mol
More
Less

BRD3731 Property

Boiling point:
529.3±50.0 °C(Predicted)
Density 
1.15±0.1 g/cm3(Predicted)
pka
15.22±0.60(Predicted)
form 
Solid
color 
Light yellow to yellow
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

ChemScene
Product number
CS-0087099
Product name
(R)-BRD3731
Purity
98.22%
Packaging
5mg
Price
$550
Updated
2021/12/16
ChemScene
Product number
CS-0087099
Product name
(R)-BRD3731
Purity
98.22%
Packaging
10mg
Price
$880
Updated
2021/12/16
ChemScene
Product number
CS-0087099
Product name
(R)-BRD3731
Purity
98.22%
Packaging
50mg
Price
$1950
Updated
2021/12/16
ChemScene
Product number
CS-0087099
Product name
(R)-BRD3731
Purity
98.22%
Packaging
100mg
Price
$2950
Updated
2021/12/16
More
Less

BRD3731 Chemical Properties,Usage,Production

Description

BRD3731 is a selective GSK3β inhibitor, with IC50s of 15 nM and 215 nM for GSK3β and GSK3α, respectively. It displays 14-fold selectivity for GSK3β. BRD3731 displays reduced potency towards the GSK3β (D133E), with an IC50 = 53 nM compared to GSK3β (wt) (cf. IC50 = 15 nM). Moreover, BRD3731 inhibits GSK3β with a Kd of 3.3 μM in cellular context. In addition, BRD3731 is a GSK3β- selective inhibitor from patent US20160375006A1, compound example 272.

BRD3731 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

BRD3731 Suppliers

Wuhan chuang he chemical co. LTD
Tel
15907120073
Fax
15527109962
Email
1261789306@qq.com
Country
China
ProdList
1168
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24644
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11974
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
cindy.huang@synzest.com
Country
China
ProdList
12000
Advantage
58
RD International Technology Co., Limited
Tel
18024082417
Email
market@ubiochem.com
Country
China
ProdList
9266
Advantage
58
Henan Tianfu Chemical Co.,Ltd.
Tel
+86-0371-55170693 +86-19937530512
Fax
0371-55170693
Email
info@tianfuchem.com
Country
China
ProdList
21632
Advantage
55
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58

2056262-08-7, BRD3731Related Search:


  • BRD3731
  • BRD3731 (BRD-3731
  • (R)-BRD3731
  • 5H-Pyrazolo[3,4-b]quinolin-5-one, 3-(2,2-dimethylpropyl)-1,2,4,6,7,8-hexahydro-4,7,7-trimethyl-4-phenyl-, (4R)-
  • 2056262-08-7