ChemicalBook > CAS DataBase List > BRD3731
BRD3731
- Product Name
- BRD3731
- CAS No.
- 2056262-08-7
- Chemical Name
- BRD3731
- Synonyms
- BRD3731;(R)-BRD3731;BRD3731 (BRD-3731;5H-Pyrazolo[3,4-b]quinolin-5-one, 3-(2,2-dimethylpropyl)-1,2,4,6,7,8-hexahydro-4,7,7-trimethyl-4-phenyl-, (4R)-
- CBNumber
- CB84667683
- Molecular Formula
- C24H31N3O
- Formula Weight
- 377.52
- MOL File
- 2056262-08-7.mol
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BRD3731 Property
- Boiling point:
- 529.3±50.0 °C(Predicted)
- Density
- 1.15±0.1 g/cm3(Predicted)
- pka
- 15.22±0.60(Predicted)
- form
- Solid
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0087099
- Product name
- (R)-BRD3731
- Purity
- 98.22%
- Packaging
- 5mg
- Price
- $550
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0087099
- Product name
- (R)-BRD3731
- Purity
- 98.22%
- Packaging
- 10mg
- Price
- $880
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0087099
- Product name
- (R)-BRD3731
- Purity
- 98.22%
- Packaging
- 50mg
- Price
- $1950
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0087099
- Product name
- (R)-BRD3731
- Purity
- 98.22%
- Packaging
- 100mg
- Price
- $2950
- Updated
- 2021/12/16
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BRD3731 Chemical Properties,Usage,Production
Description
BRD3731 is a selective GSK3β inhibitor, with IC50s of 15 nM and 215 nM for GSK3β and GSK3α, respectively. It displays 14-fold selectivity for GSK3β. BRD3731 displays reduced potency towards the GSK3β (D133E), with an IC50 = 53 nM compared to GSK3β (wt) (cf. IC50 = 15 nM). Moreover, BRD3731 inhibits GSK3β with a Kd of 3.3 μM in cellular context. In addition, BRD3731 is a GSK3β- selective inhibitor from patent US20160375006A1, compound example 272.
BRD3731 Preparation Products And Raw materials
Raw materials
Preparation Products
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BRD3731 Suppliers
- Tel
- +1-+1(833)-552-7181
- sales@aladdinsci.com
- Country
- United States
- ProdList
- 52924
- Advantage
- 58