ChemicalBook > CAS DataBase List > 8-Bromo-3'-deoxy-3'-fluoroguanosine

8-Bromo-3'-deoxy-3'-fluoroguanosine

Product Name
8-Bromo-3'-deoxy-3'-fluoroguanosine
CAS No.
847649-50-7
Chemical Name
8-Bromo-3'-deoxy-3'-fluoroguanosine
Synonyms
8-Bromo-3'-deoxy-3'-fluoroguanosine;8-Bromo-3’-deoxy-3’-fluoroguanosine;Guanosine, 8-?bromo-?3'-?deoxy-?3'-?fluoro- (9CI);2-amino-8-bromo-9-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one
CBNumber
CB84672494
Molecular Formula
C10H11BrFN5O4
Formula Weight
364.13
MOL File
847649-50-7.mol
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8-Bromo-3'-deoxy-3'-fluoroguanosine Property

Boiling point:
728.1±70.0 °C(Predicted)
Density 
2.53±0.1 g/cm3(Predicted)
pka
12.34±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

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8-Bromo-3'-deoxy-3'-fluoroguanosine Chemical Properties,Usage,Production

Uses

8-Bromo-3’-deoxy-3’-fluoroguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

8-Bromo-3'-deoxy-3'-fluoroguanosine Preparation Products And Raw materials

Raw materials

Preparation Products

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8-Bromo-3'-deoxy-3'-fluoroguanosine Suppliers

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847649-50-7, 8-Bromo-3'-deoxy-3'-fluoroguanosineRelated Search:


  • 8-Bromo-3'-deoxy-3'-fluoroguanosine
  • Guanosine, 8-?bromo-?3'-?deoxy-?3'-?fluoro- (9CI)
  • 8-Bromo-3’-deoxy-3’-fluoroguanosine
  • 2-amino-8-bromo-9-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one
  • 847649-50-7