ChemicalBook > CAS DataBase List > MRT 68921 dihydrochloride

MRT 68921 dihydrochloride

Product Name: MRT 68921 dihydrochloride
CAS No.: 2080306-21-2
Chemical Name: MRT 68921 dihydrochloride
Synonyms: MRT 68921 dihydrochloride;MRT 68921 HYDROCHLORIDE;MRT68921 HYDROCHLORIDE;inhibit,MRT 68921,ULK,MRT-68921 dihydrochloride,Inhibitor,MRT68921,Unc-51 like kinase,MRT68921 dihydrochloride,MRT-68921;N-[3-({5-cyclopropyl-2-[(2-methyl-1,2,3,4-tetrahydroisoquinolin-6-yl)amino]pyrimidin-4-yl}amino)propyl]cyclobutanecarboxamide dihydrochloride
CBNumber: CB84673507
Molecular Formula: C25H35ClN6O
Formula Weight: 471.05
MOL File: 2080306-21-2.mol

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MRT 68921 dihydrochloride Property

storage temp.: Store at -20°C
solubility: Soluble in H2O:33.3(Max Conc. mg/mL);65.6(Max Conc. mM)
form: Solid
color: White to off-white
Water Solubility: Soluble to 100 mM in water

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 5780
Product name: MRT68921dihydrochloride
Purity: ≥98%(HPLC)
Packaging: 25
Price: $402
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FM172881
Product name: MRT 68921 dihydrochloride
Packaging: 25mg
Price: $800
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FM172881
Product name: MRT 68921 dihydrochloride
Packaging: 50mg
Price: $1400
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FM172881
Product name: MRT 68921 dihydrochloride
Packaging: 10mg
Price: $400
Updated: 2021/12/16

DC Chemicals

Product number: DC23194
Product name: MRT-68921hydrochloride
Purity: >98%
Packaging: 1g
Price: $1450
Updated: 2021/12/16

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MRT 68921 dihydrochloride Chemical Properties,Usage,Production

Description

MRT68921 is an inhibitor of ULK1 and ULK2 (IC50s = 2.9 and 1.1 nM, respectively).

Uses

MRT68921 dihydrochloride is a potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively[1].

target

MRT68921 dihydrochloride is a potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively.

storage

Desiccate at RT

References

[1] Petherick KJ, et al. Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy. J Biol Chem. 2015 May 1;290(18):11376-83. DOI:10.1074/jbc.C114.627778

MRT 68921 dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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2080306-21-2, MRT 68921 dihydrochlorideRelated Search:

MRT 68921 HYDROCHLORIDE;MRT68921 HYDROCHLORIDE

MRT 68921 dihydrochloride

N-[3-({5-cyclopropyl-2-[(2-methyl-1,2,3,4-tetrahydroisoquinolin-6-yl)amino]pyrimidin-4-yl}amino)propyl]cyclobutanecarboxamide dihydrochloride

inhibit,MRT 68921,ULK,MRT-68921 dihydrochloride,Inhibitor,MRT68921,Unc-51 like kinase,MRT68921 dihydrochloride,MRT-68921

2080306-21-2