Eltoprazine Dihydrochloride
- Product Name
- Eltoprazine Dihydrochloride
- CAS No.
- 143485-51-2
- Chemical Name
- Eltoprazine Dihydrochloride
- Synonyms
- Eltoprazine 2HCl;Eltoprazine Dihydrochloride;Eltoprazine dihydrochloride, 10 mM in DMSO;1-(2,3-Dihydro-1,4-benzodioxin-5-yl)piperazine Dihydrochloride
- CBNumber
- CB84673552
- Molecular Formula
- C12H17ClN2O2
- Formula Weight
- 256.73
- MOL File
- 143485-51-2.mol
Eltoprazine Dihydrochloride Property
- Melting point:
- 257 °C(dec.)
- form
- powder to crystal
- color
- White to Light yellow to Light orange
Safety
- HS Code
- 2934.99.3000
N-Bromosuccinimide Price
- Product number
- E1357
- Product name
- Eltoprazine Dihydrochloride
- Packaging
- 10MG
- Price
- $136
- Updated
- 2025/07/31
- Product number
- E1357
- Product name
- Eltoprazine Dihydrochloride
- Packaging
- 50MG
- Price
- $485
- Updated
- 2025/07/31
- Product number
- 37867
- Product name
- Eltoprazinedihydrochloride,≥98%(HPLC)
- Purity
- ≥98%(HPLC)
- Packaging
- 50MG
- Price
- $666.27
- Updated
- 2021/12/16
- Product number
- 37867
- Product name
- Eltoprazinedihydrochloride,98%(HPLC)
- Purity
- 98%(HPLC)
- Packaging
- 10MG
- Price
- $164.64
- Updated
- 2021/12/16
Eltoprazine Dihydrochloride Chemical Properties,Usage,Production
Uses
Eltoprazine (DU 28853) dihydrochloride is a 5-HT1A/5-HT1B receptors agonist and a 5-HT2C receptor antagonist. Eltoprazine dihydrochloride shows antiaggressive and anxiogenic effects[1][2].
in vivo
Rats are chronically treated with Mianserin (10 mg/kg i.p.) or Eltoprazine (1 mg/kg i.p.) and are tested in the elevated plus-maze test for anxiety. Mianserin and Eltoprazine display opposite effects in the elevated plus-maze: Mianserin induces anxiolytic-like effects, while Eltoprazine shows anxiogenic-like ones[2].
References
[1] Sijbesma H, et al. Eltoprazine, a drug which reduces aggressive behaviour, binds selectively to 5-HT1 receptor sites in the rat brain: an autoradiographic study. Eur J Pharmacol. 1990 Feb 20;177(1-2):55-66. DOI:10.1016/0014-2999(90)90549-l
[2] Rocha B, et al. Chronic mianserin or eltoprazine treatment in rats: effects on the elevated plus-maze test and on limbic 5-HT2C receptor levels. Eur J Pharmacol. 1994 Sep 1;262(1-2):125-31. DOI:10.1016/0014-2999(94)90035-3
Eltoprazine Dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Eltoprazine Dihydrochloride Suppliers
- Tel
- 0731-85526065 13308475853
- ivy@hnhbsj.com
- Country
- China
- ProdList
- 7247
- Advantage
- 62
- Tel
- 03-36680489
- Fax
- 03-3668-0520
- Sales-JP@TCIchemicals.com
- Country
- Japan
- ProdList
- 28387
- Advantage
- 80
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 021-67121386, 800-988-0390
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 5391
- Advantage
- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- 86-571-88216897,88216896 13588875226
- Fax
- 86-571-88216895
- sales@hzclap.com
- Country
- CHINA
- ProdList
- 6312
- Advantage
- 58
- Tel
- 2537653158 16621191650
- Fax
- QQ 2537653158
- 2537653158@qq.com
- Country
- China
- ProdList
- 7299
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing@energy-chemical.com
- Country
- China
- ProdList
- 44918
- Advantage
- 58