ChemicalBook > CAS DataBase List > LJ570
LJ570
- Product Name
- LJ570
- CAS No.
- 2252488-69-8
- Chemical Name
- LJ570
- Synonyms
- LJ570;LJ570, 10 mM in DMSO;1,1'-Biphenyl]-4-propanoic acid,α-([1,1'-biphenyl]-4-yloxy)-,(αS)-;[1,1'-Biphenyl]-4-propanoic acid, α-([1,1'-biphenyl]-4-yloxy)-, (αS)-;(2S)-2-{[1,1'-biphenyl]-4-yloxy}-3-{[1,1'-biphenyl]-4-yl}propanoic acid;inhibit,Peroxisome proliferator-activated receptors,LJ-570,LJ 570,LJ570,Inhibitor,PPAR
- CBNumber
- CB84676593
- Molecular Formula
- C27H22O3
- Formula Weight
- 394.47
- MOL File
- 2252488-69-8.mol
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LJ570 Property
- Boiling point:
- 601.0±55.0 °C(Predicted)
- Density
- 1.185±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 2.96±0.10(Predicted)
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N-Bromosuccinimide Price
DC Chemicals
- Product number
- DC33576
- Product name
- LJ570
- Packaging
- 100mg
- Price
- $800
- Updated
- 2021/12/16
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LJ570 Chemical Properties,Usage,Production
Description
LJ570 is the first PPARα/γ Dual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation. LJ570 is a potent partial agonist of both PPARα and γ subtypes. LJ570 inhibited the Cdk5-mediated phosphorylation of PPARγ at serine 273 that is currently considered the mechanism by which some PPARγ partial agonists exert antidiabetic effects similar to thiazolidinediones, without showing their typical side effects. LJ570 may be useful for treatment of dyslipidemic type 2 diabetes.
target
LJ570 is the first PPARα/γ Dual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation.
LJ570 Preparation Products And Raw materials
Raw materials
Preparation Products
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LJ570 Suppliers
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