(3-BROMOACETYL)COUMARIN Property

Melting point:

164-168 °C (lit.)

Boiling point:

424.6±45.0 °C(Predicted)

Density 

1.674±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Room Temperature

form 

powder to crystal

color 

White to Orange to Green

λmax

363nm(MeOH)(lit.)

CAS DataBase Reference

29310-88-1(CAS DataBase Reference)

Safety

Hazard Codes 

Xn

Risk Statements 

22-41

Safety Statements 

26-36/39

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

2932209090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P501Dispose of contents/container to..…

(3-BROMOACETYL)COUMARIN Chemical Properties,Usage,Production

Uses

3-(bromoacetyl)coumarin may be used in the synthesis of the following:

• 3-(bromoacetyl)coumarin oxime via reaction with hydroxylamine hydrochloride in methanol
• 3-(bromoacetyl)coumarin-O-methyloxime via reaction with O-benzylhydroxylammonium chloride/diluted HCl in methanol
• 3-(bromoacetyl)coumarin-O-benzyloxime via reaction with O-benzyl hydroxylamine hydrochloride in methanol
• 3-[2′-(2′′-arylidenehydrazinyl)thiazolyl]coumarins via reaction with benzaldehyde thiosemicarbazones

General Description

3-(Bromoacetyl)coumarin can be synthesized via the bromination of 3-acetylcoumarin in chloroform.