BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE
- Product Name
- BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE
- CAS No.
- 23749-58-8
- Chemical Name
- BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE
- Synonyms
- luminor2;luminogren;luminophor2;Yellow 2GF;Fluorescein T;AHR agonist 3;7H-Benzimidazo[2;yellow-green490rt;Solvent Yellow 184;LABOTEST-BB LT00007121
- CBNumber
- CB8476272
- Molecular Formula
- C18H10N2O
- Formula Weight
- 270.28
- MOL File
- 23749-58-8.mol
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE Property
- Melting point:
- 189 °C
- Boiling point:
- 613.6±38.0 °C(Predicted)
- Density
- 1.40±0.1 g/cm3(Predicted)
- pka
- 2.05±0.20(Predicted)
- form
- powder
- color
- Bright yellow
- InChI
- InChI=1S/C18H10N2O/c21-18-13-8-4-6-11-5-3-7-12(16(11)13)17-19-14-9-1-2-10-15(14)20(17)18/h1-10H
- InChIKey
- NZBSAAMEZYOGBA-UHFFFAOYSA-N
- SMILES
- C12=NC3=CC=CC=C3N1C(=O)C1=CC=CC3=CC=CC2=C13
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
N-Bromosuccinimide Price
- Product number
- S51021
- Product name
- BENZO(DE)BENZO(4,5)IMIDAZO(2,1-A)ISOQUINOLIN-7-ONE
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $143
- Updated
- 2025/07/31
- Product number
- S51021
- Product name
- BENZO(DE)BENZO(4,5)IMIDAZO(2,1-A)ISOQUINOLIN-7-ONE
- Purity
- Aldrich
- Packaging
- 10mg
- Price
- $139
- Updated
- 2024/03/01
- Product number
- B6583
- Product name
- 7H-Benzimidazo[2,1-a]benz[de]isoquinolin-7-one
- Purity
- min. 98.0 %
- Packaging
- 5G
- Price
- $113
- Updated
- 2025/07/31
- Product number
- B6583
- Product name
- 7H-Benzimidazo[2,1-a]benz[de]isoquinolin-7-one
- Purity
- min. 98.0 %
- Packaging
- 25G
- Price
- $339
- Updated
- 2025/07/31
- Product number
- CHM0028499
- Product name
- BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE
- Purity
- 95.00%
- Packaging
- 100G
- Price
- $2717.48
- Updated
- 2021/12/16
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE Chemical Properties,Usage,Production
Uses
AHR agonist 3 is an aryl hydrocarbon receptor (AhR) agonist, that can induces cell cycle arrest or apoptosis via activation of tumor-suppressive transcriptional programs. AHR agonist 3 inhibits triple-negative breast cancer (TNBC) stem cell growth via AhR while exhibits minimal cytotoxicity against normal human primary cells and can be used for cancer research[1].
Properties and Applications
|
TEST ITEMS |
SPECIFICATION |
|
APPEARANCE |
YELLOW POWDER |
|
SHADE |
GREENISH |
|
HEAT RESISTANCE |
260 °C min |
|
LIGHT FASTNESS |
5-6 |
|
ACID RESISTANCE |
5 |
|
ALKALI RESISTANCE |
5 |
|
WATER RESISTANCE |
5 |
|
DENSITY |
1.20 g/cm 3 |
|
RESIDUE ON 80 MESH |
5.0% max |
|
WATER SOLUBLE |
1.0% max |
|
VOLATITE 105 °C |
1.0% max |
|
TINTING STRENGTH |
100-105 % |
|
WEIGHT METAL TOTAL |
50ppm max |
References
[1] Elson DJ, et.al. Induction of Aryl Hydrocarbon Receptor-Mediated Cancer Cell-Selective Apoptosis in Triple-Negative Breast Cancer Cells by a High-Affinity Benzimidazoisoquinoline. ACS Pharmacol Transl Sci. 2023 Jun 7;6(7):1028-1042. DOI:10.1021/acsptsci.2c00253
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE manufacturers
- Product
- Solvent Yellow 184 23749-58-8
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2021-10-09
- Product
- Solvent Yellow 184 23749-58-8
- Price
- US $10.00/Kg/Bag
- Min. Order
- 1Kg/Bag
- Purity
- 99%
- Supply Ability
- 20 Tons
- Release date
- 2021-10-18