ChemicalBook > CAS DataBase List > 4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl

4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl

Product Name: 4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
CAS No.: 2154342-45-5
Chemical Name: 4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
Synonyms: Poma-C3-NH2·HCl;Pomalidomide-C3-NH2 HCl;Pomalidomide-C3-amine HCl;Thalidomide-NH-C4-NH2 HCl;Pomalidomide 4'-alkylC3-amine;Pomalidomide 4'-alkylC3-amine hydrochloride;4-(3-aminopropylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl;4-((3-Aminopropyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride;4-[(3-aminopropyl)amino]-2-(2,6-dioxopiperidin-3- yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride
CBNumber: CB84796316
Molecular Formula: C16H19ClN4O4
Formula Weight: 366.79946
MOL File: 2154342-45-5.mol

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4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Property

storage temp.: Store at -20°C
form: Solid
color: Off-white to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H312Harmful in contact with skin

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Acrotein

Product number: AS00952
Product name: 4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dioneHCl
Purity: 97%
Packaging: 1g
Price: $660
Updated: 2021/12/16

Acrotein

Product number: AS00952
Product name: 4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dioneHCl
Purity: 97%
Packaging: 0.25g
Price: $1100
Updated: 2021/12/16

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4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Chemical Properties,Usage,Production

Uses

Pomalidomide-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].

IC 50

Cereblon

storage

Store at -20°C

References

[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Pomalidomide-C3-NH2 hydrochloride 2154342-45-5
Price: US $0.00/mg
Min. Order: 100mg
Purity: >99.00%
Supply Ability: 100mg
Release date: 2024-04-01

2154342-45-5, 4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HClRelated Search:

4-[(4-Aminobutyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Pomalidomide-C6-NH2?hydrochloride 1H-Isoindole-1,3(2H)-dione, 4-[(2-aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- 4-((4-azidobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione -alkylC5-amine 6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexanoic acid Poma-C8-N3

4-[(3-Aminopropyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl

4-((3-Aminopropyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride

4-[(3-aminopropyl)amino]-2-(2,6-dioxopiperidin-3- yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride

Thalidomide-NH-C4-NH2 HCl

Inhibitor,E3 Ligase Ligand-Linker Conjugates,inhibit,Pomalidomide C3 NH2 hydrochloride,Pomalidomide-C-3-NH2 hydrochloride,PomalidomideC3NH2 hydrochloride

Pomalidomide 4'-alkylC3-amine hydrochloride

Poma-C3-NH2·HCl

Pomalidomide-C3-amine HCl

4-((3-Aminopropyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride , Pomalidomide-C3-NH2 HCl

4-(3-aminopropylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione

Pomalidomide 4'-alkylC3-amine

Pomalidomide-C3-NH2 HCl

2154342-45-5