IACS-8968

Product Name: IACS-8968
CAS No.: 2144425-14-7
Chemical Name: IACS-8968
Synonyms: IACS-8968;IDO/TDO Inhibitor;IACS 8968,IACS8968;1,3,8-Triazaspiro[4.5]decane-2,4-dione, 6,6-dimethyl-8-[7-(trifluoromethyl)imidazo[1,5-a]pyridin-5-yl]-
CBNumber: CB84797070
Molecular Formula: C17H18F3N5O2
Formula Weight: 381.35
MOL File: 2144425-14-7.mol

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IACS-8968 Property

Density: 1.55±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:50.0(Max Conc. mg/mL);131.11(Max Conc. mM)
form: Solid
pka: 9.95±0.40(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0043587
Product name: IACS-8968
Purity: 98.13%
Packaging: 1mg
Price: $250
Updated: 2021/12/16

ChemScene

Product number: CS-0043587
Product name: IACS-8968
Purity: 98.13%
Packaging: 5mg
Price: $750
Updated: 2021/12/16

ChemScene

Product number: CS-0043587
Product name: IACS-8968
Purity: 98.13%
Packaging: 10mg
Price: $1200
Updated: 2021/12/16

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IACS-8968 Chemical Properties,Usage,Production

Uses

IACS-8968 (IDO/TDO Inhibitor) is a dual IDO and TDO inhibitor, with pIC50s of 6.43 for IDO and <5 for TDO, respectively.

References

[1] ARYL SULFONOHYDRAZIDES. WO 2017189386 A1
[2] Hamilton MM, Mseeh F, McAfoos TJ, et al. Discovery of IACS-9779 and IACS-70465 as Potent Inhibitors Targeting Indoleamine 2,3-Dioxygenase 1 (IDO1) Apoenzyme. J Med Chem. 2021;64(15):11302-11329. DOI:10.1021/acs.jmedchem.1c00679

IACS-8968 Preparation Products And Raw materials

Raw materials

Preparation Products

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IACS-8968 Suppliers

China 7 United States 4 Global 11

TargetMol Chemicals Inc.

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TargetMol Chemicals Inc.

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Aladdin Scientific

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2144425-14-7, IACS-8968Related Search:

IACS-8968

IDO/TDO Inhibitor

1,3,8-Triazaspiro[4.5]decane-2,4-dione, 6,6-dimethyl-8-[7-(trifluoromethyl)imidazo[1,5-a]pyridin-5-yl]-

IACS 8968,IACS8968

2144425-14-7

C17H18F3N5O2