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Benzyl (S)-2-(cyanomethyl)piperazine-1-carboxylate

Product Name
Benzyl (S)-2-(cyanomethyl)piperazine-1-carboxylate
CAS No.
2158302-01-1
Chemical Name
Benzyl (S)-2-(cyanomethyl)piperazine-1-carboxylate
Synonyms
(S)-benzyl 2-(cyanomethyl)piperazine-1-carboxylate;Benzyl (S)-2-(cyanomethyl)piperazine-1-carboxylate hydrochloride;(S)-1-Cbz-2-(cyanomethyl)piperazine;Sildenafil Impurity 61 Hydrochloride;Benzyl 2-(cyanomethyl)piperazine-1-carboxylate;Benzyl (S)-2-(Cyanomethyl)piperazine-1-carboxylate;benzyl (2S)-2-(cyanomethyl)piperazine-1-carboxylate;Benzyl ( S )-2-( cyanomethyl ) piperazine - l - carboxylate;1-benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate;1-Piperazinecarboxylic acid, 2-(cyanomethyl)-, phenylmethyl ester, (2S)-
CBNumber
CB84800866
Molecular Formula
C14H17N3O2
Formula Weight
259.3
MOL File
2158302-01-1.mol
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Benzyl (S)-2-(cyanomethyl)piperazine-1-carboxylate Property

Boiling point:
450.9±30.0 °C(Predicted)
Density 
1.163±0.06 g/cm3(Predicted)
storage temp. 
RT, protect from light
pka
7.69±0.40(Predicted)
Appearance
Colorless to light yellow Viscous liquid
InChI
InChI=1S/C14H17N3O2/c15-7-6-13-10-16-8-9-17(13)14(18)19-11-12-4-2-1-3-5-12/h1-5,13,16H,6,8-11H2/t13-/m0/s1
InChIKey
QSKMFYCQRQLYMF-ZDUSSCGKSA-N
SMILES
N1(C(OCC2=CC=CC=C2)=O)CCNC[C@@H]1CC#N
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0095743
Product name
Benzyl(S)-2-(cyanomethyl)piperazine-1-carboxylate
Purity
≥97.0%
Packaging
100mg
Price
$68
Updated
2021/12/16
ChemScene
Product number
CS-0095743
Product name
Benzyl(S)-2-(cyanomethyl)piperazine-1-carboxylate
Purity
≥97.0%
Packaging
250mg
Price
$122
Updated
2021/12/16
ChemScene
Product number
CS-0095743
Product name
Benzyl(S)-2-(cyanomethyl)piperazine-1-carboxylate
Purity
≥97.0%
Packaging
1g
Price
$265
Updated
2021/12/16
Chemenu
Product number
CM328382
Product name
benzyl(2S)-2-(cyanomethyl)piperazine-1-carboxylate
Purity
95+%
Packaging
5g
Price
$990
Updated
2021/12/16
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Benzyl (S)-2-(cyanomethyl)piperazine-1-carboxylate Chemical Properties,Usage,Production

Synthesis

To a solution of I-benzyl 4-tert-butyl (2S)-2-(cyanomethyl) piperazine-1,4-dicarboxylate (6.0 g, 1.0 eq) in dioxane (20.8 mL) was added 4.0 M HCl in dioxane (20.8 mL, 5.0 eq). The mixture was stirred at 20 °C for 1 hour. Then NaHCO3 was added to the reaction mixture until pH>7, after which the reaction was concentrated under reduced pressure to remove dioxane. The residue was diluted with H2O (50 mL) and extracted with ethyl acetate (50 mLx3). The combined organic layers were washed with H2O (20 mL), dried over Na2SO4, filtered, and concentrated under reduced pressure to give a residue. The product benzyl (2S)-2- (cyanomethyl) piperazine-1-carboxylate (4.1 g, 95% yield) was obtained as a yellow oil.

Benzyl (S)-2-(cyanomethyl)piperazine-1-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Benzyl (S)-2-(cyanomethyl)piperazine-1-carboxylate manufacturers

Suzhou Nordica Biopharma CO.,LTD
Product
benzyl (2S)-2-(cyanomethyl)piperazine-1-carboxylate 2158302-01-1
Price
US $0.00-0.00/g
Min. Order
0.005g
Purity
0.99
Supply Ability
1 tons
Release date
2024-11-15
Zhejiang J&C Biological Technology Co.,Limited
Product
Benzyl (S)-2-(cyanomethyl)piperazine-1-carboxylate 2158302-01-1
Price
US $0.00/gram
Min. Order
1gram
Purity
99%
Supply Ability
10kg
Release date
2022-02-17

2158302-01-1, Benzyl (S)-2-(cyanomethyl)piperazine-1-carboxylateRelated Search:


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  • 1-benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate
  • benzyl (2S)-2-(cyanomethyl)piperazine-1-carboxylate
  • Benzyl 2-(cyanomethyl)piperazine-1-carboxylate
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  • 2158302-01-1