1808113-09-8

Product Name: 1808113-09-8
CAS No.: 1808113-09-8
Chemical Name: 1808113-09-8
Synonyms: Corin;Corin, 10 mM in DMSO;Benzenebutanamide, N-[4-[(1R,2S)-2-aminocyclopropyl]phenyl]-4-[[(2-aminophenyl)amino]carbonyl]-, rel-
CBNumber: CB84804556
Molecular Formula: C26H28N4O2
Formula Weight: 428.53
MOL File: 1808113-09-8.mol

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1808113-09-8 Property

Boiling point:: 631.8±55.0 °C(Predicted)
Density: 1.287±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 100 mg/mL (233.36 mM);Water : < 0.1 mg/mL (insoluble)
form: Solid
pka: 13.32±0.70(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological

Product number: 024423
Product name: Corin
Packaging: 96Tests
Price: $715
Updated: 2021/12/16

Usbiological

Product number: 471917
Product name: Corin
Packaging: 96Tests
Price: $731
Updated: 2021/12/16

Usbiological

Product number: 154187
Product name: Corin
Packaging: 10ug
Price: $356
Updated: 2021/12/16

ChemScene

Product number: CS-0034060
Product name: Corin
Purity: 98.75%
Packaging: 5mg
Price: $550
Updated: 2021/12/16

ChemScene

Product number: CS-0034060
Product name: Corin
Purity: 98.75%
Packaging: 10mg
Price: $850
Updated: 2021/12/16

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1808113-09-8 Chemical Properties,Usage,Production

Uses

Corin is a dual inhibitor of histone lysine specific demethylase (LSD1) and histone deacetylase (HDAC), with a Ki(inact) of 110 nM for LSD1 and an IC50 of 147 nM for HDAC1.

References

[1] Kalin JH, et al. Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors. Nat Commun. 2018 Jan 4;9(1):53. DOI:10.1038/s41467-017-02242-4

1808113-09-8 Preparation Products And Raw materials

Raw materials

Preparation Products

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1808113-09-8 Suppliers

China 31 United States 4 Global 35

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1808113-09-8, 1808113-09-8Related Search:

Corin

Benzenebutanamide, N-[4-[(1R,2S)-2-aminocyclopropyl]phenyl]-4-[[(2-aminophenyl)amino]carbonyl]-, rel-

Corin, 10 mM in DMSO

1808113-09-8