ST3932

Product Name: ST3932
CAS No.: 1246018-21-2
Chemical Name: ST3932
Synonyms: ST3932;ST-3932,ST3932;9H-Purine-2-propanol, 6-amino-α,9-dimethyl-8-(2H-1,2,3-triazol-2-yl)-
CBNumber: CB84805795
Molecular Formula: C12H16N8O
Formula Weight: 288.32
MOL File: 1246018-21-2.mol

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ST3932 Property

Boiling point:: 482.7±55.0 °C(Predicted)
Density: 1.62±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 14.96±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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ST3932 Chemical Properties,Usage,Production

Description

ST3932 is a metabolite of ST1535, acts as an antagonist of adenosine A2A receptor, with Kis of 8 nM and 33 nM for A2A and A1 receptors, respectively.

ST3932 is a metabolite of ST1535, acts as an antagonist of adenosine A2A receptor, with Kis of 8 nM and 33 nM for A2A and A1 receptors, respectively. ST3932 inhibits agonist-induced cAMP accumulation with an IC50 value of 450 nM[1].

ST3932 (10, 20, 40 mg/kg, p.o.) antagonizes haloperidol-induced catalepsy, and increases motor activity in mice. ST3932 (20, 40 mg/kg, i.p.) significantly increases the number of contralateral turns induced by l-DOPA in rats[1].

References

[1]. ST3932, et al. Animal models of Parkinson?s disease: Effects of two adenosine A2A receptor antagonists ST4206 and ST3932, metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535). Eur J Pharmacol. 2015 Aug 15;761:353-61.

ST3932 Preparation Products And Raw materials

Raw materials

Preparation Products

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ST3932 Suppliers

China 5 United States 3 Global 8

Twochem Co.Ltd.

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1246018-21-2, ST3932Related Search:

ST3932

ST-3932,ST3932

9H-Purine-2-propanol, 6-amino-α,9-dimethyl-8-(2H-1,2,3-triazol-2-yl)-

1246018-21-2