ChemicalBook > CAS DataBase List > FDL169

FDL169

Product Name: FDL169
CAS No.: 1628416-28-3
Chemical Name: FDL169
Synonyms: FDL169;CFTR corrector 2;FDL169; FDL-169; FDL 169;CFTR corrector 2, 10 mM in DMSO;2(1H)-Phthalazineacetamide, 7-ethoxy-4-(3-fluorophenyl)-N-methyl-N-(2-methyl-6-benzoxazolyl)-1-oxo-;2-(7-Ethoxy-4-(3-fluorophenyl)-1-oxophthalazin-2(1H)-yl)-N-methyl-N-(2-methylbenzo[d]oxazol-6-yl)acetamide;2-[7-Ethoxy-4-(3-fluorophenyl)-1-oxo-2(1H)-phthalazinyl]-N-methyl-N-(2-methyl-1,3-benzoxazol-6-yl)acetamide;2-[7-ethoxy-4-(3-fluorophenyl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-methyl-N-(2-methyl-1,3-benzoxazol-6-yl)acetamide;Inhibitor,CFTR,CFTR corrector2,CFTR corrector-2,Autophagy,Cystic fibrosis transmembrane conductance regulator,CFTR corrector 2,inhibit
CBNumber: CB84808620
Molecular Formula: C27H23FN4O4
Formula Weight: 486.49
MOL File: 1628416-28-3.mol

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FDL169 Property

Boiling point:: 664.9±65.0 °C(Predicted)
Density: 1.34±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO:33.0(Max Conc. mg/mL);67.83(Max Conc. mM)
Ethanol:8.0(Max Conc. mg/mL);16.44(Max Conc. mM)
pka: 0.91±0.30(Predicted)
form: Solid
color: White to off-white
InChI: InChI=1S/C27H23FN4O4/c1-4-35-20-9-10-21-22(14-20)27(34)32(30-26(21)17-6-5-7-18(28)12-17)15-25(33)31(3)19-8-11-23-24(13-19)36-16(2)29-23/h5-14H,4,15H2,1-3H3
InChIKey: XRPSUWYWZUQALB-UHFFFAOYSA-N
SMILES: C1(=O)C2=C(C=CC(OCC)=C2)C(C2=CC=CC(F)=C2)=NN1CC(N(C)C1C=C2OC(C)=NC2=CC=1)=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0091038
Product name: CFTRcorrector2
Purity: 99.85%
Packaging: 5mg
Price: $220
Updated: 2021/12/16

ChemScene

Product number: CS-0091038
Product name: CFTRcorrector2
Purity: 99.85%
Packaging: 10mg
Price: $330
Updated: 2021/12/16

ChemScene

Product number: CS-0091038
Product name: CFTRcorrector2
Purity: 99.85%
Packaging: 50mg
Price: $950
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611967
Product name: FDL-169
Purity: >98%
Packaging: 250mg
Price: $1356.6
Updated: 2021/12/16

ChemScene

Product number: CS-0091038
Product name: CFTRcorrector2
Purity: 99.85%
Packaging: 100mg
Price: $1500
Updated: 2021/12/16

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FDL169 Chemical Properties,Usage,Production

Uses

CFTR corrector 2 is a cystic fibrosis transmembrane conductance corrector (CFTR), extracted from patent US20140274933[1].

References

[1] Bridget M. Cole, et al. PHTHALAZINONE COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS. US20140274933.

FDL169 Preparation Products And Raw materials

Raw materials

Preparation Products

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1628416-28-3, FDL169Related Search:

FDL169

2(1H)-Phthalazineacetamide, 7-ethoxy-4-(3-fluorophenyl)-N-methyl-N-(2-methyl-6-benzoxazolyl)-1-oxo-

CFTR corrector 2

FDL169; FDL-169; FDL 169

2-[7-Ethoxy-4-(3-fluorophenyl)-1-oxo-2(1H)-phthalazinyl]-N-methyl-N-(2-methyl-1,3-benzoxazol-6-yl)acetamide

2-[7-ethoxy-4-(3-fluorophenyl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-methyl-N-(2-methyl-1,3-benzoxazol-6-yl)acetamide

Inhibitor,CFTR,CFTR corrector2,CFTR corrector-2,Autophagy,Cystic fibrosis transmembrane conductance regulator,CFTR corrector 2,inhibit

2-(7-Ethoxy-4-(3-fluorophenyl)-1-oxophthalazin-2(1H)-yl)-N-methyl-N-(2-methylbenzo[d]oxazol-6-yl)acetamide

CFTR corrector 2, 10 mM in DMSO

1628416-28-3