Cho-Arg (trifluoroacetate salt)
- Product Name
- Cho-Arg (trifluoroacetate salt)
- CAS No.
- 1609010-56-1
- Chemical Name
- Cho-Arg (trifluoroacetate salt)
- Synonyms
- Cho-Arg (trifluoroacetate salt);cholest-5-en-3-ol(3β)-3-[6-[[(2S)-2-amino-5-[(aminoiminomethyl)amino]-1-oxopentyl]amino]hexanoate],2,2,2-trifluoroacetate(1:2)
- CBNumber
- CB84814418
- Molecular Formula
- C41H70F3N5O5
- Formula Weight
- 770.04
- MOL File
- 1609010-56-1.mol
Cho-Arg (trifluoroacetate salt) Property
- storage temp.
- Store at -20°C
- solubility
- DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 25943
- Product name
- Cho-Arg (trifluoroacetate salt)
- Packaging
- 5mg
- Price
- $109
- Updated
- 2024/03/01
- Product number
- 25943
- Product name
- Cho-Arg (trifluoroacetate salt)
- Packaging
- 10mg
- Price
- $184
- Updated
- 2024/03/01
- Product number
- 25943
- Product name
- Cho-Arg (trifluoroacetate salt)
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 1538EN
- Product name
- [(4S)-4-Azaniumyl-5-[[6-[[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-oxohexyl]amino]-5-oxopentyl]-(diaminomethylidene)azanium;2,2,2-trifluoroacetate
- Packaging
- 5mg
- Price
- $218
- Updated
- 2021/12/16
- Product number
- 1538EN
- Product name
- [(4S)-4-Azaniumyl-5-[[6-[[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-oxohexyl]amino]-5-oxopentyl]-(diaminomethylidene)azanium;2,2,2-trifluoroacetate
- Packaging
- 10mg
- Price
- $302
- Updated
- 2021/12/16
Cho-Arg (trifluoroacetate salt) Chemical Properties,Usage,Production
Description
Cho-Arg is a steroid-based cationic lipid that contains a cholesterol skeleton coupled to an L-arginine head group.1 It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratios greater than or equal to 4. Cho-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence or absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin and the caveolae-mediated endocytosis inhibitor genistein . It is cytotoxic to H1299 cells (IC50 = 88.5 μg/ml).
References
1. Sheng, R., Wang, Z., Luo, T., et al. Skeleton-
Cho-Arg (trifluoroacetate salt) Preparation Products And Raw materials
Raw materials
Preparation Products
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