3'-O-Me-G(iBu)-2'-phosphoramidite

Product Name: 3'-O-Me-G(iBu)-2'-phosphoramidite
CAS No.: 179479-04-0
Chemical Name: 3'-O-Me-G(iBu)-2'-phosphoramidite
Synonyms: 3'-O-Me-G(iBu)-2'-phosphoramidite;3’-O-Me-G(iBu)-2’-phosphoramidite;5’-O-DMTr-N2-iso-butyroyl-3’-O-methyl guanosine-2’-CED-phosphoramidite;5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-N-(2-methyl-1-oxopropyl)-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] Guanosine;Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-N-(2-methyl-1-oxopropyl)-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI);(2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-2-(2-isobutyramido-6-oxo-3,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
CBNumber: CB84842105
Molecular Formula: C45H56N7O9P
Formula Weight: 869.94
MOL File: 179479-04-0.mol

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3'-O-Me-G(iBu)-2'-phosphoramidite Chemical Properties,Usage,Production

Uses

3’-O-Me-G(iBu)-2’-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

References

[1] Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. DOI:10.1073/pnas.0631696100

3'-O-Me-G(iBu)-2'-phosphoramidite Preparation Products And Raw materials

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3'-O-Me-G(iBu)-2'-phosphoramidite Suppliers

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179479-04-0, 3'-O-Me-G(iBu)-2'-phosphoramiditeRelated Search:

3'-O-Me-G(iBu)-2'-phosphoramidite

Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-N-(2-methyl-1-oxopropyl)-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)

5’-O-DMTr-N2-iso-butyroyl-3’-O-methyl guanosine-2’-CED-phosphoramidite

5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-N-(2-methyl-1-oxopropyl)-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] Guanosine

3’-O-Me-G(iBu)-2’-phosphoramidite

(2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-2-(2-isobutyramido-6-oxo-3,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

179479-04-0