ChemicalBook > CAS DataBase List > 5-Azidomethyl-2'-beta-methyl-2',3',5'-tri-O-benzoyluridine
5-Azidomethyl-2'-beta-methyl-2',3',5'-tri-O-benzoyluridine
- Product Name
- 5-Azidomethyl-2'-beta-methyl-2',3',5'-tri-O-benzoyluridine
- CAS No.
- 2305416-08-2
- Chemical Name
- 5-Azidomethyl-2'-beta-methyl-2',3',5'-tri-O-benzoyluridine
- Synonyms
- 5-Azidomethyl-2’-β-methyl-2’,3’,5’-tri-O-benzoyluridine;5-Azidomethyl-2’-beta-methyl-2’,3’,5’-tri-O-benzoyluridine;5-Azidomethyl-2'-beta-methyl-2',3',5'-tri-O-benzoyluridine
- CBNumber
- CB84842125
- Molecular Formula
- C32H27N5O9
- Formula Weight
- 625.59
- MOL File
- 2305416-08-2.mol
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5-Azidomethyl-2'-beta-methyl-2',3',5'-tri-O-benzoyluridine Chemical Properties,Usage,Production
Uses
5-Azidomethyl-2’-beta-methyl-2’,3’,5’-tri-O-benzoyluridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1]. 5-Azidomethyl-2’-beta-methyl-2’,3’,5’-tri-O-benzoyluridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
References
[1] Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93. DOI:10.3390/molecules16097980
5-Azidomethyl-2'-beta-methyl-2',3',5'-tri-O-benzoyluridine Preparation Products And Raw materials
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