ChemicalBook > CAS DataBase List > Telratolimod

Telratolimod

Product Name: Telratolimod
CAS No.: 1359993-59-1
Chemical Name: Telratolimod
Synonyms: 3M-052;MEDI9197;Telratolimod;Telratolimod (MEDI 9197);Telratolimod, 10 mM in DMSO;N-[4-(4-amino-2-butyl-imidazo[4,5-c]quinolin-1-yl)oxybutyl]octadecanamide;N-(4-((4-Amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)oxy)butyl)stearamide;Toll-like Receptor (TLR),MEDI-9197,inhibit,Inhibitor,Telratolimod,MEDI 9197;Octadecanamide, N-[4-[(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)oxy]butyl]-
CBNumber: CB84843940
Molecular Formula: C36H59N5O2
Formula Weight: 593.89
MOL File: 1359993-59-1.mol

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Telratolimod Property

Density: 1.08±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: slightly soluble; Ethanol: slightly soluble
form: A crystalline solid
pka: 16.28±0.46(Predicted)
color: White to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0039736
Product name: Telratolimod
Purity: 99.04%
Packaging: 5mg
Price: $450
Updated: 2021/12/16

ChemScene

Product number: CS-0039736
Product name: Telratolimod
Purity: 99.04%
Packaging: 10mg
Price: $750
Updated: 2021/12/16

ChemScene

Product number: CS-0039736
Product name: Telratolimod
Purity: 99.04%
Packaging: 25mg
Price: $1500
Updated: 2021/12/16

ChemScene

Product number: CS-0039736
Product name: Telratolimod
Purity: 99.04%
Packaging: 50mg
Price: $2100
Updated: 2021/12/16

ChemScene

Product number: CS-0039736
Product name: Telratolimod
Purity: 99.04%
Packaging: 100mg
Price: $3300
Updated: 2021/12/16

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Telratolimod Chemical Properties,Usage,Production

Uses

Telratolimod (MEDI9197) is a potent toll like receptors 7/8 (TLR7/8) agonist, with antitumor activity[1].

in vivo

Telratolimod (50 μg) inhibits the tumor volume, and more potently blocks tumor gowth in combination with CpG ODN in BALB/c mice bearing CT26 colon carcinoma cells. Telratolimod (100 μg) plus 200 μg of CpG ODN slows tumor growth and prolongs survival of mice bearing large tumors^[1].

IC 50

TLR7; TLR8

References

[1] Zhao BG, et al. Combination therapy targeting toll like receptors 7, 8 and 9 eliminates large established tumors. J Immunother Cancer. 2014 May 13;2:12. DOI:10.1186/2051-1426-2-12

Telratolimod Preparation Products And Raw materials

Raw materials

Preparation Products

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Telratolimod Suppliers

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1359993-59-1, TelratolimodRelated Search:

Telratolimod

Octadecanamide, N-[4-[(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)oxy]butyl]-

3M-052

MEDI9197

N-(4-((4-Amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)oxy)butyl)stearamide

Toll-like Receptor (TLR),MEDI-9197,inhibit,Inhibitor,Telratolimod,MEDI 9197

N-[4-(4-amino-2-butyl-imidazo[4,5-c]quinolin-1-yl)oxybutyl]octadecanamide

Telratolimod, 10 mM in DMSO

Telratolimod (MEDI 9197)

1359993-59-1

C36H59N5O2