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Amino-ethyl-SS-PEG3-NHBoc

Product Name
Amino-ethyl-SS-PEG3-NHBoc
CAS No.
2144777-87-5
Chemical Name
Amino-ethyl-SS-PEG3-NHBoc
Synonyms
Amino-ethyl-SS-PEG3-NHBoc;5,8,11-Trioxa-14,15-dithia-2-azaheptadecanoic acid, 17-amino-, 1,1-dimethylethyl ester
CBNumber
CB84849528
Molecular Formula
C15H32N2O5S2
Formula Weight
384.55
MOL File
2144777-87-5.mol
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Amino-ethyl-SS-PEG3-NHBoc Property

Boiling point:
506.8±50.0 °C(Predicted)
Density 
1.133±0.06 g/cm3(Predicted)
pka
12.23±0.46(Predicted)
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Hazard and Precautionary Statements (GHS)

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Amino-ethyl-SS-PEG3-NHBoc Chemical Properties,Usage,Production

Uses

Amino-ethyl-SS-PEG3-NHBoc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC 50

Disulfide Cleavable Linker; Cleavable Linker

References

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268

Amino-ethyl-SS-PEG3-NHBoc Preparation Products And Raw materials

Raw materials

Preparation Products

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Amino-ethyl-SS-PEG3-NHBoc Suppliers

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2144777-87-5, Amino-ethyl-SS-PEG3-NHBocRelated Search:


  • Amino-ethyl-SS-PEG3-NHBoc
  • 5,8,11-Trioxa-14,15-dithia-2-azaheptadecanoic acid, 17-amino-, 1,1-dimethylethyl ester
  • 2144777-87-5
  • C15H32N2O5S2