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Ms-PEG8-t-butyl ester

Product Name
Ms-PEG8-t-butyl ester
CAS No.
2097604-01-6
Chemical Name
Ms-PEG8-t-butyl ester
Synonyms
Ms-PEG8-Boc;Ms-PEG8-t-butyl ester;4,7,10,13,16,19,22,25,28-Nonaoxa-29-thiatriacontanoic acid, 1,1-dimethylethyl ester, 29,29-dioxide
CBNumber
CB84849634
Molecular Formula
C24H48O13S
Formula Weight
576.7
MOL File
2097604-01-6.mol
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Ms-PEG8-t-butyl ester Property

Boiling point:
625.3±55.0 °C(Predicted)
Density 
1.138±0.06 g/cm3(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-24127
Product name
Ms-PEG8-t-butylester
Purity
96%
Packaging
250mg
Price
$350
Updated
2021/12/16
BroadPharm
Product number
BP-24127
Product name
Ms-PEG8-t-butylester
Purity
96%
Packaging
500mg
Price
$540
Updated
2021/12/16
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Ms-PEG8-t-butyl ester Chemical Properties,Usage,Production

Description

Ms-PEG8-t-butyl ester is a PEG linker with a mesyl group and a t-butyl protecting group. Mesyl is a good leaving group and can participate in substitution reactions. The t-butyl group can be removed under acidic condtions. The hydrophilic PEG linker increases the solubility properties of compounds in aqueous media.

Uses

Ms-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Ms-PEG8-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Ms-PEG8-t-butyl ester Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58

2097604-01-6, Ms-PEG8-t-butyl esterRelated Search:


  • Ms-PEG8-t-butyl ester
  • Ms-PEG8-Boc
  • 4,7,10,13,16,19,22,25,28-Nonaoxa-29-thiatriacontanoic acid, 1,1-dimethylethyl ester, 29,29-dioxide
  • 2097604-01-6
  • C24H48O13S