endo-BCN-PEG3-Biotin

Product Name: endo-BCN-PEG3-Biotin
CAS No.: 1263166-92-2
Chemical Name: endo-BCN-PEG3-Biotin
Synonyms: BCN-endo-PEG3-Biotin;endo-BCN-PEG3-Biotin;(1R,8S)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl 19-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-15-oxo-5,8,11-trioxa-2,14-diazanonadecanoate;5,8,11-Trioxa-2,14-diazanonadecanoic acid, 19-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-15-oxo-, (1R,8S)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester
CBNumber: CB84904722
Molecular Formula: C29H46N4O7S
Formula Weight: 594.76
MOL File: 1263166-92-2.mol

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endo-BCN-PEG3-Biotin Property

Boiling point:: 847.5±65.0 °C(Predicted)
Density: 1.25±0.1 g/cm3(Predicted)
pka: 12.05±0.46(Predicted)
form: Solid
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

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endo-BCN-PEG3-Biotin Chemical Properties,Usage,Production

Uses

BCN-PEG3-Biotin is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. BCN-PEG3-Biotin is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

Non-cleavable Linker

References

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268

endo-BCN-PEG3-Biotin Preparation Products And Raw materials

Raw materials

Preparation Products

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endo-BCN-PEG3-Biotin Suppliers

China 16 United States 2 Global 18

Xi'an Confluore Biological Technology Co., Ltd.

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View Lastest Price from endo-BCN-PEG3-Biotin manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: endo-BCN-PEG3-Biotin 1263166-92-2
Price: US $0.00/mg
Min. Order: 10mg
Purity: >95.00%
Supply Ability: 50mg
Release date: 2024-03-20

1263166-92-2, endo-BCN-PEG3-BiotinRelated Search:

endo-BCN-PEG3-Biotin

BCN-endo-PEG3-Biotin

5,8,11-Trioxa-2,14-diazanonadecanoic acid, 19-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-15-oxo-, (1R,8S)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester

(1R,8S)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl 19-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-15-oxo-5,8,11-trioxa-2,14-diazanonadecanoate

1263166-92-2

peg

ADC LINKER