4-methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid
- Product Name
- 4-methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid
- CAS No.
- 1537891-69-2
- Chemical Name
- 4-methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid
- Synonyms
- 4-Methyl-4-(2-pyridinyldithio)pentanoic acid;Pentanoic acid, 4-methyl-4-(2-pyridinyldithio)-
- CBNumber
- CB84920553
- Molecular Formula
- C11H15NO2S2
- Formula Weight
- 257.37
- MOL File
- 1537891-69-2.mol
4-methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid Property
- Boiling point:
- 416.1±41.0 °C(Predicted)
- Density
- 1.25±0.1 g/cm3(Predicted)
- pka
- 4.54±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
4-methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid Chemical Properties,Usage,Production
Uses
4-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
IC 50
Disulfide Cleavable Linker; Cleavable Linker
References
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
4-methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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