trans-nerolidol
- Product Name
- trans-nerolidol
- CAS No.
- 40716-66-3
- Chemical Name
- trans-nerolidol
- Synonyms
- 1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl-, (E)-;TRANS-NEROLIDOL;E-Nerolidol;(E)-Nerolidol;(6E)-3,7,11-Trimethyldodeca-1,6,10-trien-3-ol;trans-Nerolidal solution;trans-Form;Nerolidol (E);Einecs 255-053-4;Trans-(E)-Nerolidol
- CBNumber
- CB8497598
- Molecular Formula
- C15H26O
- Formula Weight
- 222.37
- MOL File
- 40716-66-3.mol
trans-nerolidol Property
- Boiling point:
- 145-146 °C12 mm Hg(lit.)
- Density
- 0.876 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.479(lit.)
- Flash point:
- 230 °F
- storage temp.
- -20°C
- solubility
- DMF: miscible,DMSO: miscible,Ethanol: miscible,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
- pka
- 14.40±0.29(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
- Odor
- at 100.00 %. floral green citrus woody waxy
- Odor Type
- floral
- JECFA Number
- 1646
- Merck
- 13,6501
- BRN
- 5731231
- Stability:
- Light Sensitive
- LogP
- 5.316 (est)
- NIST Chemistry Reference
- 1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl-, (e)-(40716-66-3)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- R751405
- Product name
- TRANS-NEROLIDOL
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $143
- Updated
- 2025/07/31
- Product number
- 18143
- Product name
- trans-Nerolidol
- Purity
- analyticalstandard
- Packaging
- 100mg
- Price
- $84
- Updated
- 2025/07/31
- Product number
- 04610590
- Product name
- trans-Nerolidol
- Purity
- primary pharmaceutical reference standard
- Packaging
- 50mg
- Price
- $406
- Updated
- 2025/07/31
- Product number
- CRM40742
- Product name
- trans-Nerolidal solution
- Purity
- certified reference material, 2000?μg/mL in methanol, ampule of 1?mL
- Packaging
- 1mL
- Price
- $95.2
- Updated
- 2022/05/15
- Product number
- 25778
- Product name
- trans-Nerolidol
- Packaging
- 50mg
- Price
- $27
- Updated
- 2024/03/01
trans-nerolidol Chemical Properties,Usage,Production
Description
trans-Nerolidol is a sesquiterpene that has been found in various plants, including C. sativa, and has diverse biological activities, including antimicrobial, antioxidant, anticancer, and insecticidal properties. In a disc assay, trans-nerolidol inhibits the growth of S. aureus, B. subtilis, E. coli, and S. cerevisiae with zones of inhibition measuring 10, 9, 10, and 4 mm, respectively. It reduces viability of CaCo-2 adenocarcinoma cells with an IC50 value of 28.7 mg/L and reduces production of reactive oxygen species (ROS). trans-Nerolidol is insecticidal against A. aegypti larvae with a 24-hour LC50 value of 9 mg/L.
Occurrence
Reported to be found in cabreuva oil, oil of neroli, balsam Peru, ylang ylang and many others (Gildemeister & Hoffman, 1959).
Uses
Nerolidol (cas# 40716-66-3) is a terpene standard found in cannabis.
Preparation
By isolation from a suitable essential oil or by chemical synthesis.
Definition
ChEBI: Nerolidol is a farnesane sesquiterpenoid that is dodeca-1,6,10-triene which carries methyl groups at positions 3, 7 and 11 and a hydroxy group at position 3. It is a natural product that is present in various flowers and plants with a floral odor. Chemically, it exists in two geometric isomers, trans and cis forms. It is widely used in cosmetics (e.g. shampoos and perfumes), in non-cosmetic products (e.g. detergents and cleansers) and also as a food flavoring agent. It has a role as a flavouring agent, a cosmetic, a pheromone, a neuroprotective agent, an antifungal agent, an anti-inflammatory agent, an antihypertensive agent, an antioxidant, a volatile oil component, an insect attractant and a herbicide. It is a farnesane sesquiterpenoid, a tertiary allylic alcohol and a volatile organic compound.
References
[1] LORENZO NISSEN . Characterization and antimicrobial activity of essential oils of industrial hemp varieties (Cannabis sativa L.)[J]. Fitoterapia, 2010, 81 5: Pages 413-419. DOI: 10.1016/j.fitote.2009.11.010
[2] H D SKALTSA. Composition and antimicrobial activity of the essential oil of Scutellaria albida ssp. albida from Greece.[J]. Planta medica, 2000, 66 7: 672-674. DOI: 10.1055/s-2000-8650
[3] MARTIN AMBRO?. The Influence of Sesquiterpenes from Myrica rubra on the Antiproliferative and Pro-Oxidative Effects of Doxorubicin and Its Accumulation in Cancer Cells.[J]. Molecules, 2015, 20 8: 15343-15358. DOI: 10.3390/molecules200815343
[4] J. CHANTRAINE. Insecticidal activity of essential oils on Aedes aegypti larvae[J]. Phytotherapy Research, 1998, 64 3. DOI: 10.1002/(sici)1099-1573(199808)12:5<350::aid-ptr311>3.0.co;2-7
trans-nerolidol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from trans-nerolidol manufacturers
- Product
- Nerolidol 40716-66-3
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2024-12-13
- Product
- Nerolidol 40716-66-3
- Price
- US $1.00/kg
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2018-12-21