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Nerolidol

Product Name
Nerolidol
CAS No.
40716-66-3
Chemical Name
Nerolidol
Synonyms
1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl-, (E)-;E-Nerolidol;(E)-Nerolidol;(6E)-3,7,11-Trimethyldodeca-1,6,10-trien-3-ol;trans-Nerolidal solution;Nerolidol;trans-Form;Nerolidol (E);Einecs 255-053-4;Trans-(E)-Nerolidol
CBNumber
CB8497598
Molecular Formula
C15H26O
Formula Weight
222.37
MOL File
40716-66-3.mol
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Nerolidol Property

Boiling point:
145-146 °C12 mm Hg(lit.)
Density 
0.876 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.479(lit.)
Flash point:
230 °F
storage temp. 
-20°C
solubility 
DMF: miscible,DMSO: miscible,Ethanol: miscible,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
pka
14.40±0.29(Predicted)
Odor
at 100.00 %. floral green citrus woody waxy
Odor Type
floral
JECFA Number
1646
Merck 
13,6501
BRN 
5731231
Stability:
Light Sensitive
LogP
5.316 (est)
NIST Chemistry Reference
1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl-, (e)-(40716-66-3)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
1
10-23
Toxicity
Both the acute oral LD50 in rats and the acute dermal LD50 in rabbits exceeded 5 g/kg (Russell. 1973).
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
18143
Product name
trans-Nerolidol
Purity
analyticalstandard
Packaging
100mg
Price
$81.5
Updated
2024/03/01
Sigma-Aldrich
Product number
04610590
Product name
trans-Nerolidol
Purity
primary pharmaceutical reference standard
Packaging
50mg
Price
$158.8
Updated
2024/03/01
Sigma-Aldrich
Product number
CRM40742
Product name
trans-Nerolidal solution
Purity
certified reference material, 2000?μg/mL in methanol, ampule of 1?mL
Packaging
1mL
Price
$95.2
Updated
2022/05/15
Cayman Chemical
Product number
25778
Product name
trans-Nerolidol
Packaging
50mg
Price
$27
Updated
2024/03/01
Cayman Chemical
Product number
25778
Product name
trans-Nerolidol
Packaging
100mg
Price
$48
Updated
2024/03/01
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Nerolidol Chemical Properties,Usage,Production

Description

trans-Nerolidol is a sesquiterpene that has been found in various plants, including C. sativa, and has diverse biological activities, including antimicrobial, antioxidant, anticancer, and insecticidal properties. In a disc assay, trans-nerolidol inhibits the growth of S. aureus, B. subtilis, E. coli, and S. cerevisiae with zones of inhibition measuring 10, 9, 10, and 4 mm, respectively. It reduces viability of CaCo-2 adenocarcinoma cells with an IC50 value of 28.7 mg/L and reduces production of reactive oxygen species (ROS). trans-Nerolidol is insecticidal against A. aegypti larvae with a 24-hour LC50 value of 9 mg/L.

Occurrence

Reported to be found in cabreuva oil, oil of neroli, balsam Peru, ylang ylang and many others (Gildemeister & Hoffman, 1959).

Uses

Nerolidol (cas# 40716-66-3) is a terpene standard found in cannabis.

Preparation

By isolation from a suitable essential oil or by chemical synthesis.

Definition

ChEBI: Nerolidol is a farnesane sesquiterpenoid that is dodeca-1,6,10-triene which carries methyl groups at positions 3, 7 and 11 and a hydroxy group at position 3. It is a natural product that is present in various flowers and plants with a floral odor. Chemically, it exists in two geometric isomers, trans and cis forms. It is widely used in cosmetics (e.g. shampoos and perfumes), in non-cosmetic products (e.g. detergents and cleansers) and also as a food flavoring agent. It has a role as a flavouring agent, a cosmetic, a pheromone, a neuroprotective agent, an antifungal agent, an anti-inflammatory agent, an antihypertensive agent, an antioxidant, a volatile oil component, an insect attractant and a herbicide. It is a farnesane sesquiterpenoid, a tertiary allylic alcohol and a volatile organic compound.

Nerolidol Preparation Products And Raw materials

Raw materials

Preparation Products

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Nerolidol Suppliers

Hangzhou J&H Chemical Co., Ltd.
Tel
+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
10015
Advantage
53
Originchem Co., Ltd
Tel
0523-0523-86200346 15996028822
Fax
0523-86200341
Email
1583458435@qq.com
Country
China
ProdList
63
Advantage
58
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6011
Advantage
61
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14059
Advantage
65
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5654
Advantage
65
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4941
Advantage
60
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3989
Advantage
66
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7854
Advantage
58
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View Lastest Price from Nerolidol manufacturers

Career Henan Chemical Co
Product
Nerolidol 40716-66-3
Price
US $1.00/kg
Min. Order
1g
Purity
99%
Supply Ability
100KG
Release date
2018-12-21

40716-66-3, NerolidolRelated Search:


  • Teprenone Impurity 19
  • trans-Nerolidal solution
  • (6E)-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol
  • 1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl-, (E)-
  • Trans-(E)-Nerolidol
  • 3-Hydroxy-3,7,11-trimethyl-1,6,10-dodecatriene
  • Nerolidol
  • (E)-3,7,11-trimethyldodeca-1,6,10-trien-3-ol
  • nerolidol,(6E)-3,7,11-trimethyl-1,6,10-dodecatrien-3-ol,peruviol,trans-nerolidol
  • 1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl-, (6E)-
  • (6E)-3,7,11-Trimethyldodeca-1,6,10-trien-3-ol
  • TRANS-NEROLIDOL WITH GC
  • (E)-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol, trans-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol
  • (E)-3,7,11-Trimethyldodeca-1,6,10-triene-3-ol
  • (E)-Nerolidol
  • E-Nerolidol
  • [R,Z,(-)]-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol
  • Einecs 255-053-4
  • Nerolidol (E)
  • Nerolidol trans-form
  • trans-Nerolidol,(E)-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol, trans-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol
  • trans-Form
  • Teprenone Impurity 19 (trans-Nerolidol)
  • Teprenone Impurity 2 (trans-Nerolidol)
  • 40716-66-3