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NALOXONE METHIODIDE

Product Name
NALOXONE METHIODIDE
CAS No.
93302-47-7
Chemical Name
NALOXONE METHIODIDE
Synonyms
NALOXONE METHIODIDE QUATERNARY SALT OF N A;(17R)-17-allyl-4,5α-epoxy-3,14-dihydroxy-17-methyl-6-oxo-morphinanium iodide;(5α,17r)-4,5-epoxy-3,14-dihydroxy-17-methyl-6-oxo-17-(2-propenyl)-morphinanium iodide;N-Methylnaloxonium iodide, (5α,17R)-4,5-Epoxy-3,14-dihydroxy-17-methyl-6-oxo-17-(2-propenyl)-morphinanium iodide
CBNumber
CB8503976
Molecular Formula
C20H24NO4.I
Formula Weight
469.313
MOL File
93302-47-7.mol
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NALOXONE METHIODIDE Property

storage temp. 
2-8°C
solubility 
H2O: soluble
form 
solid
color 
tan
Water Solubility 
H2O: >10mg/mL
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N129
Product name
Naloxone methiodide
Purity
≥98% (HPLC), solid
Packaging
25mg
Price
$103.55
Updated
2025/07/31
Sigma-Aldrich
Product number
N129
Product name
Naloxone methiodide
Purity
≥98% (HPLC), solid
Packaging
100mg
Price
$328
Updated
2025/07/31
Sigma-Aldrich
Product number
N129
Product name
Naloxone methiodide
Purity
≥98% (HPLC), solid
Packaging
250mg
Price
$682
Updated
2025/07/31
American Custom Chemicals Corporation
Product number
API0008287
Product name
NALOXONE METHIODIDE
Purity
95.00%
Packaging
25MG
Price
$621.41
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008287
Product name
NALOXONE METHIODIDE
Purity
95.00%
Packaging
100MG
Price
$772.53
Updated
2021/12/16
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NALOXONE METHIODIDE Chemical Properties,Usage,Production

Uses

Naloxone methiodide has been used as inhibitor of opioid receptor in fish and mice. Naloxone methiodide has been used to block opioid neurotransmission.

Biochem/physiol Actions

Naloxone methiodide has low affinity for opioid receptors than naloxone. Administration of naloxone inhibits opioid receptor and opioid-induced respiratory depression.

in vivo

Naloxone‐methiodide (10 mg/mL; 200 μL; i.p.), induces abdominal hypersensitivity in IL-10?/? mice with colitis[2].

Animal Model:Ten- to twelve-week-old IL-10 gene-deficient male (IL-10?/?) mice on C57BL/6 genetic background[2]
Dosage:10 mg/mL; 200 μL
Administration:Intraperitoneally
Result:In piroxicam-treated IL-10?/? mice induced abdominal pain.

NALOXONE METHIODIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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NALOXONE METHIODIDE Suppliers

Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Merck KGaA
Tel
21-20338288
Email
ordercn@merckgroup.com
Country
China
ProdList
6394
Advantage
58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
Advantage
58
Santa Cruz Biotechnology Inc
Tel
021-60936350
Email
scbt@scbt.com
Country
China
ProdList
6594
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58

93302-47-7, NALOXONE METHIODIDERelated Search:


  • (17R)-17-allyl-4,5α-epoxy-3,14-dihydroxy-17-methyl-6-oxo-morphinanium iodide
  • NALOXONE METHIODIDE QUATERNARY SALT OF N A
  • (5α,17r)-4,5-epoxy-3,14-dihydroxy-17-methyl-6-oxo-17-(2-propenyl)-morphinanium iodide
  • N-Methylnaloxonium iodide, (5α,17R)-4,5-Epoxy-3,14-dihydroxy-17-methyl-6-oxo-17-(2-propenyl)-morphinanium iodide
  • 93302-47-7